Protein Alignment Dll and nkx2.3

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_571498.1
• Gene: nkx2.3 / 30698
• ZFINID: ZDB-GENE-990415-178
• Length: 321
• Species: Danio rerio
• Alignment Length: 260
• Identity: 70/260 - (26%)
• Similarity: 99/260 - (38%)
• Gaps: 62/260 - (23%)

  Fly    59 GGQDSGFPSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPP---KDDFSISDKCEDSGLRVNG- 119
            ||...||......:.:......|:|...   .|.:||....|   ..|..:.|:.||...:..|
Zfish    57 GGDSPGFSDNEEKMSFLNSLSMQDSLVE---SSLSPPMFVHPALGHVDTKLEDELEDHETKSCGA 118

  Fly   120 -------------------KGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQ 165
                               :.:..||||.::|..|:.:|.|||::.:||:.|||..||::|.||.
Zfish   119 ILRTPECEAEVHSDTERAQRQRTRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASTLKLTS 183

  Fly   166 TQVKIWFQNRRSKYK-----KMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGELANGRFLWA 225
            |||||||||||.|.|     |.::.|                  |.|.|....       |....
Zfish   184 TQVKIWFQNRRYKCKRQRQDKTLEMA------------------GHHHPPPPR-------RVAVP 223

  Fly   226 ALETNGTLALVHSTGGNNGGGSNSGSPSHYLPPGHSP---TPSSTPVSELSPEFPPTGLSPPTQA 287
            .|..:|...|   ||..:...:.:.:|..|...|:|.   ...:.|.|...|..||...:..|.|
Zfish   224 VLVRDGKPCL---TGSQSYNTTYAVNPGPYTYNGYSSYNNAAYTNPYSCTYPSLPPLPANTSTNA 285

  Fly   288  287
            Zfish   286  285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	33/60 (55%)
nkx2.3	NP_571498.1	Homeodomain	143..199	CDD:459649	32/55 (58%)