Protein Alignment Dll and nkx2.7

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_571494.1
• Gene: nkx2.7 / 30694
• ZFINID: ZDB-GENE-990415-179
• Length: 269
• Species: Danio rerio
• Alignment Length: 277
• Identity: 76/277 - (27%)
• Similarity: 120/277 - (43%)
• Gaps: 56/277 - (20%)

  Fly    21 SVTPGI-------NIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGG------QDSGFPSPRSAL 72
            ::.||:       ::|.:|..::..|:..:     ||....:.|:.|      :...|...||:.
Zfish    24 ALNPGVFMGVEQDSVPLQSLQLQCMQNTLS-----RSLDLLYSPEKGIPGEQVKCDDFDIVRSSC 83

  Fly    73 GYPF-PPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQL 136
            |.|. ..|..|..:..        |   |..|.|.|.|..:: ||...|.:..||||.::|..|:
Zfish    84 GSPTEEEMDANEETSM--------C---PFTDSSYSSKNGET-LREKPKQRLRRKPRVLFSQTQV 136

  Fly   137 QQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGG 201
            .:|.|||::.:||:.|||..||.:|.||.|||||||||||.|.|:..:       :..:.|.|
Zfish   137 FELERRFKQQRYLSAPERDHLALALKLTSTQVKIWFQNRRYKCKRQRQ-------DKSLELAG-- 192

  Fly   202 PNPGQHS-PNQMHSGELANGRFLWAALETNGTLALVHSTGGNNGGGSNSGSPSHYLPPGHSPTPS 265
              |.:.: |..:..|:..:|      ...|.|::..:    ||...|...:|.|.   ..:..||
Zfish   193 --PRRVAVPVLVRDGKPCHG------APYNVTVSYPY----NNYYNSYGNNPYHC---NFTSVPS 242

  Fly   266 STPVSELSPEFPPTGLS 282
            ....|::...|....|:
Zfish   243 FANTSQIPNHFVDMNLT 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	32/55 (58%)
nkx2.7	NP_571494.1	COG5576	87..210	CDD:227863	49/145 (34%)
		Homeodomain	125..181	CDD:459649	32/55 (58%)