Protein Alignment Dll and en2a

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_571119.2
• Gene: en2a / 30243
• ZFINID: ZDB-GENE-980526-167
• Length: 265
• Species: Danio rerio
• Alignment Length: 197
• Identity: 51/197 - (25%)
• Similarity: 71/197 - (36%)
• Gaps: 68/197 - (34%)

  Fly    47 GIRSTYQHFGPQGGQ-DSGFPSPRSALGY--------------PFPPMHQN-------------S 83
            |.|..:...||..|| .|..|:..::..:              |..|..:|             |
Zfish    69 GARENHNPTGPSTGQVGSTVPAEEASTTHTSSGGKEAEIESEEPLKPRGENVDQCLGSESDSSQS 133

  Fly    84 YSGYHLG------------------SYAPPCASPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTI 130
            .|....|                  |..|....|.|...|..||                :|||.
Zfish   134 NSNGQTGQGMLWPAWVYCTRYSDRPSSGPRSRKPKKKAASKEDK----------------RPRTA 182

  Fly   131 YSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGM 195
            :::.|||:|...||..:||....|..||..|||.::|:||||||:|:|.||      ..|..:|:
Zfish   183 FTAEQLQRLKAEFQTNRYLTEQRRQSLAQELGLNESQIKIWFQNKRAKIKK------ASGVKNGL 241

  Fly   196 PL 197
            .:
Zfish   242 AI 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	26/55 (47%)
en2a	NP_571119.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..142		14/72 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..180		7/40 (18%)
		Homeodomain	177..233	CDD:459649	27/71 (38%)
		Engrail_1_C_sig	234..264	CDD:431338	2/10 (20%)