Protein Alignment Dll and Tlx3

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: XP_036012630.1
• Gene: Tlx3 / 27140
• MGIID: 1351209
• Length: 338
• Species: Mus musculus
• Alignment Length: 238
• Identity: 71/238 - (29%)
• Similarity: 100/238 - (42%)
• Gaps: 64/238 - (26%)

  Fly     3 APDAPHTPKYMDGGNTAASVTPGINIPGKSAFVEL-----QQHAAAGYGGIRSTYQHFGPQGGQ- 61
            :|..|..|..|:.  .|::.||..:.|......::     |..|.|..|...::|.. ||.||:
Mouse    38 SPAQPFRPPRMEA--PASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLG-GPPGGRP 99

  Fly    62 DSGFPS-PRSALGYPFPPMHQNSYSGYHLGSYAP------------PCASPP------------- 100
            .:.:|| |.|..|...|.....||| .:| |.||            |.|.||
Mouse   100 GAAYPSLPASFAGLGAPFEDAGSYS-VNL-SLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVP 162

  Fly   101 --------------------KDDFSISDKCEDSGL--RV-----NGKGKKMRKPRTIYSSLQLQQ 138
                                ||.|:.:.......:  |:     |....|.:||||.:|.:|:.:
Mouse   163 TVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICE 227

  Fly   139 LNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKK 181
            |.:||.|.:|||..|||.||.||.:|..|||.||||||:|:::
Mouse   228 LEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRR 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	31/55 (56%)
Tlx3	XP_036012630.1	PRK07764	<20..>109	CDD:236090	20/73 (27%)
		Homeodomain	214..270	CDD:459649	31/55 (56%)