Protein Alignment Dll and Shox2

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_037160.2
• Gene: Shox2 / 25546
• RGDID: 3674
• Length: 331
• Species: Rattus norvegicus
• Alignment Length: 315
• Identity: 84/315 - (26%)
• Similarity: 115/315 - (36%)
• Gaps: 66/315 - (20%)

  Fly    13 MDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSPRSALGYPFP 77
            ::.|....:..||...||:.........||.|.||........|..||...|..:...|.|...|
  Rat    29 LESGPLRGAKEPGCVEPGRDDRSSPAVRAAGGGGGAGGGGGGGGGGGGGAGGGGAGGGAGGGRSP 93

  Fly    78 PMHQNSYSGYHLGSYAPPCASPPKDDFS--ISDKCEDS-GLRVNGKGK-KMRKPRTIYSSLQLQQ 138
            ....:  .|....|..|  .||...:.|  :.|:.||: |:...|:.| |.|:.||.::..||.:
  Rat    94 VRELD--MGAAERSREP--GSPRLTEVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNE 154

  Fly   139 LNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGPN 203
            |.|.|..|.|.....|.||:..|||::.:|::||||||:|.:|
  Rat   155 LERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRK---------------------- 197

  Fly   204 PGQHSPNQMHSGELANGRFLWAALETN-----GTLALVHSTGGNNGGGSNSGSPSHYLPPGHSPT 263
                ..||:|.|.|......:.|....     |.|.:...            ..||.     :.|
  Rat   198 ----QENQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQ------------QDSHC-----NVT 241

  Fly   264 PSSTPV-SELSPEFPPTGLSPPTQAPWDQKPHWIDHKPPPQMTPQPPH--PAATL 315
            |.|..| ::|..:      |....|.....||...| .|..|.|.||.  |.|||
  Rat   242 PLSFQVQAQLQLD------SAVAHAHHHLHPHLAAH-APYMMFPAPPFGLPLATL 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	24/55 (44%)
Shox2	NP_037160.2	Homeodomain	141..197	CDD:459649	24/55 (44%)
		OAR	311..327	CDD:461067