Protein Alignment Dll and Tlx1

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: XP_006526978.1
• Gene: Tlx1 / 21908
• MGIID: 98769
• Length: 345
• Species: Mus musculus
• Alignment Length: 211
• Identity: 64/211 - (30%)
• Similarity: 88/211 - (41%)
• Gaps: 49/211 - (23%)

  Fly     4 PDAPHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSP 68
            |..|..|  ..||..|.|:.|   :|| |..|.:......|.|         |..||..:|....
Mouse    79 PGGPGGP--AGGGGGACSMGP---LPG-SYNVNMALAGGPGPG---------GGGGGGGAGGAGA 128

  Fly    69 RSALGYPFPPMHQNSYSG-----YHLGSYAPPCASPP-----------------------KDDFS 105
            .||.|....|.|: ..:|     ..|.:..|...|.|                       ||.|:
Mouse   129 LSAAGVIRVPAHR-PLAGAVAHPQPLATGLPTVPSVPAVPGVNNLTGLTFPWMESNRRYTKDRFT 192

  Fly   106 ISDKCEDSGLRV-----NGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQ 165
            ::........|:     |....|.:||||.::.||:.:|.:||.|.:|||..|||.||.:|.:|.
Mouse   193 VALSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTD 257

  Fly   166 TQVKIWFQNRRSKYKK 181
            .|||.||||||:|:::
Mouse   258 AQVKTWFQNRRTKWRR 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	30/55 (55%)
Tlx1	XP_006526978.1	Homeodomain	217..273	CDD:459649	30/55 (55%)