Protein Alignment Dll and Nkx2-9

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_032727.2
• Gene: Nkx2-9 / 18094
• MGIID: 1270158
• Length: 235
• Species: Mus musculus
• Alignment Length: 214
• Identity: 65/214 - (30%)
• Similarity: 83/214 - (38%)
• Gaps: 66/214 - (30%)

  Fly   105 SISDKCEDSGLRVNGKG---KKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQT 166
            |.:|..:.:.||....|   :|.||.|.::|..|..:|.|||::.:||:.|||.:||..|.||.|
Mouse    59 SPADSSQLASLRRESPGSDPEKRRKRRVLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPT 123

  Fly   167 QVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGELANGRFLWAALETNG 231
            ||||||||.|.|.|:                   |..||...|:.|     |....|.||   .|
Mouse   124 QVKIWFQNHRYKLKR-------------------GRAPGITEPSDM-----AASSDLHAA---PG 161

  Fly   232 TL------ALVHS-TGGNNGGGSNSGSPSHYLPPGHSPTPSSTPVSELSPEFPPTG--------- 280
            .|      .|||. ...|||.|.           |.|..|.....:.|:...|..|
Mouse   162 LLRRVVVPVLVHDRPPSNNGRGE-----------GTSAVPQDKCSARLATACPVPGYTAFGPGSA 215

  Fly   281 ---------LSPPTQAPWD 290
                     |:||....|:
Mouse   216 LGLFPAYQHLAPPALVSWN 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	30/55 (55%)
Nkx2-9	NP_032727.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..86		8/26 (31%)
		Homeodomain	82..138	CDD:459649	30/55 (55%)