Protein Alignment Dll and DLX3

DIOPT Version :9

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 120/328 - (36%)
• Similarity: 144/328 - (43%)
• Gaps: 125/328 - (38%)

  Fly    59 GGQDSGFPS-PRSA---LGYPFPPMHQNSYSG-----------YH----------LGSYAPPC-- 96
            |.:||  |: |.|:   |||...|.| :.|||           ||          .|:|:|..
Human    25 GSKDS--PTLPESSVTDLGYYSAPQH-DYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEY 86

  Fly    97 ---AS------------PPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRT 146
               ||            |.:|..|:.::.|.....||||.||:|||||||||.||..|.||||:.
Human    87 TYGASYRQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKA 151

  Fly   147 QYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQ 211
            |||||||||||||.||||||||||||||||||:||:.|       |..:||        :||||
Human   152 QYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK-------NGEVPL--------EHSPN- 200

  Fly   212 MHSGELANGRFLWAALETNGTLALVHSTGGNNGGGSNSGSPSHYLPPGHSP-----TPSSTPV-- 269
                                                ||.|.:...||  ||     :..|||.
Human   201 ------------------------------------NSDSMACNSPP--SPALWDTSSHSTPAPA 227

  Fly   270 -SELSPEFP----PTGLSPPTQAPWDQKPHWIDHKPPPQMTPQPPHPAATLHPQTHHH---NPPP 326
             |:|.|..|    |:.|..||.: |    :...:...|.:..|||.||      |.||   .|||
Human   228 RSQLPPPLPYSASPSYLDDPTNS-W----YHAQNLSGPHLQQQPPQPA------TLHHASPGPPP 281

  Fly   327 QMG 329
            ..|
Human   282 NPG 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeobox	127..180	CDD:278475	45/52 (87%)
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39		6/15 (40%)
		DLL_N	27..107	CDD:403572	21/82 (26%)
		COG5576	<109..232	CDD:227863	76/176 (43%)
		homeobox	129..188		49/58 (84%)
		Homeobox	132..186	CDD:395001	45/53 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		37/148 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153149
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I4345
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1416398at2759
OrthoFinder	1	1.000	-	-		FOG0000655
OrthoInspector	1	1.000	-	-		otm40491
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.900