Protein Alignment Dll and DLX1

DIOPT Version :9

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_835221.2
• Gene: DLX1 / 1745
• HGNCID: 2914
• Length: 255
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 109/277 - (39%)
• Similarity: 136/277 - (49%)
• Gaps: 67/277 - (24%)

  Fly    18 TAASVTPGINIP--GKSAFVEL----QQHAAA----GYGGIRSTYQ--HFGPQGGQD--SGFPSP 68
            |..::...:|.|  ||:.|:|.    ||.:.:    |:..:...:.  |..|.|...  |.|..|
Human     2 TMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASSFSRP 66

  Fly    69 RSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSG-------------LRVNGK 120
               ||||:    .||.|.:....|.....|.|........:.||.|             :|.|||
Human    67 ---LGYPY----VNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVRFNGK 124

  Fly   121 GKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMK- 184
            |||:|||||||||||||.||||||:|||||||||||||||||||||||||||||:|||:||:||
Human   125 GKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQ 189

  Fly   185 ---AAQGPGTNSGMPLGGGGPN-PGQHSPNQMHSGELANGRFLWAALETNGTLALVHSTGGNNGG 245
               |.:|....:|..|..|.|. |...:||.                          |:|..:||
Human   190 GGAALEGSALANGRALSAGSPPVPPGWNPNS--------------------------SSGKGSGG 228

  Fly   246 GSNSGSPSH--YLPPGH 260
            .:.|..||:  :.|..|
Human   229 NAGSYIPSYTSWYPSAH 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeobox	127..180	CDD:278475	49/52 (94%)
DLX1	NP_835221.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		9/35 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..118		3/22 (14%)
		Homeobox	131..185	CDD:395001	49/53 (92%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..230		10/51 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153144
Domainoid	1	1.000	109	1.000	Domainoid score	I6359
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1416398at2759
OrthoFinder	1	1.000	-	-		FOG0000655
OrthoInspector	1	1.000	-	-		otm40491
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24327
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X884
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.900