Protein Alignment Dll and Hoxd4

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_034599.2
• Gene: Hoxd4 / 15436
• MGIID: 96208
• Length: 250
• Species: Mus musculus
• Alignment Length: 239
• Identity: 67/239 - (28%)
• Similarity: 92/239 - (38%)
• Gaps: 53/239 - (22%)

  Fly     4 PDAPHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQH--FG--PQGGQDSG 64
            |..|...:|:.||.....   |.:..|..|     |.|.....|:   |..  ||  |.||   |
Mouse    15 PKFPPCEEYLQGGYLGEQ---GADYYGSGA-----QGADFQPSGL---YPRPDFGEQPFGG---G 65

  Fly    65 FPSPRSAL---GYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCED-------------- 112
            .|.|.|||   |:...|    |..|.|.|:....|.:||......:..|..
Mouse    66 GPGPGSALPARGHGQEP----SGPGSHYGAPGERCPAPPPAPLPGARACSQPTGPKQPPPGTALK 126

  Fly   113 --------------SGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGL 163
                          :.:..|..|.:.::.||.|:..|:.:|.:.|...:||....|.|:|.:|.|
Mouse   127 QPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCL 191

  Fly   164 TQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGPNPGQH 207
            ::.|:||||||||.|:||..|.....|.:|..........||||
Mouse   192 SERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSCSSSAAPGQH 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	23/55 (42%)
Hoxd4	NP_034599.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..126		28/112 (25%)
		Antp-type hexapeptide	131..136		0/4 (0%)
		Homeodomain	153..209	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..250		7/26 (27%)