Protein Alignment Dll and Hoxc8

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_034596.1
• Gene: Hoxc8 / 15426
• MGIID: 96198
• Length: 242
• Species: Mus musculus
• Alignment Length: 214
• Identity: 61/214 - (28%)
• Similarity: 80/214 - (37%)
• Gaps: 52/214 - (24%)

  Fly    10 PKYMD-------GGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPS 67
            |.|.|       |.:.|....||.:.||   |.....|.        ..:.|.|..|..:||:..
Mouse    21 PAYYDCRFPQSVGRSHALVYGPGGSAPG---FQHASHHV--------QDFFHHGTSGISNSGYQQ 74

  Fly    68 PRSAL----------GYPFPPMHQNSYSGYHLGSYA--PPCASPPKDDFSISDKCEDSG------ 114
            ...:|          ||...| .|:.|......|..  |.|.|....:.|     |..|
Mouse    75 NPCSLSCHGDASKFYGYEALP-RQSLYGAQQEASVVQYPDCKSSANTNSS-----EGQGHLNQNS 133

  Fly   115 --------LRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIW 171
                    :|.:..|:  |..|..||..|..:|.:.|....||....|.|::.:||||:.|||||
Mouse   134 SPSLMFPWMRPHAPGR--RSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIW 196

  Fly   172 FQNRRSKYKKMMKAAQGPG 190
            |||||.|:||.....:.||
Mouse   197 FQNRRMKWKKENNKDKLPG 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	26/55 (47%)
Hoxc8	NP_034596.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		8/46 (17%)
		Antp-type hexapeptide	138..143		0/4 (0%)
		Homeodomain	150..206	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		3/10 (30%)