Protein Alignment Dll and Hoxa2

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_034581.1
• Gene: Hoxa2 / 15399
• MGIID: 96174
• Length: 372
• Species: Mus musculus
• Alignment Length: 323
• Identity: 86/323 - (26%)
• Similarity: 125/323 - (38%)
• Gaps: 87/323 - (26%)

  Fly    18 TAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSPRSALGYP-FPPMHQ 81
            |..|:.||.:          .:| .||.||...:    .|.|.:  |.|.|..||..| :|.|.:
Mouse    55 TIPSLNPGSH----------PRH-GAGVGGRPKS----SPAGSR--GSPVPAGALQPPEYPWMKE 102

  Fly    82 NSYSGYHLGSYAPPCASPP-------KDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQL 139
            ...:   ..:..||.|:..       |:...|:|          |.|...|:.||.|::.||.:|
Mouse   103 KKAA---KKTALPPAAASTGPACLGHKESLEIAD----------GSGGGSRRLRTAYTNTQLLEL 154

  Fly   140 NRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTN------------ 192
            .:.|...:||..|.|.|:||.|.||:.|||:||||||.|:|:..:..:...:.
Mouse   155 EKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKFKNLEDSDKV 219

  Fly   193 ----------------SGMPLGGGGPNPGQHSPNQM-----HSGE---------LANGRFLWAAL 227
                            ||..|...|....|::.:|.     |:|:         .:|.:.|....
Mouse   220 EEDEEEKSLFEQALSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQTFPVSPLTSNEKNLKHFQ 284

  Fly   228 ETNGTLALVHSTGGNN-GGGSNSGSPSHYLPPGHS-----PTPSSTPVSE-LSPEFPPTGLSP 283
            ..:.|:....||.|.| |.|.|:.||.....|...     .|.|...:|: |||..|.:..||
Mouse   285 HQSPTVPNCLSTMGQNCGAGLNNDSPEAIEVPSLQDFNVFSTDSCLQLSDALSPSLPGSLDSP 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	28/55 (51%)
Hoxa2	NP_034581.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..95		16/56 (29%)
		Antp-type hexapeptide	96..101		1/4 (25%)
		Homeodomain	140..196	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..225		1/30 (3%)