Protein Alignment Dll and GSC

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_776248.1
• Gene: GSC / 145258
• HGNCID: 4612
• Length: 257
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 48/191 - (25%)
• Similarity: 77/191 - (40%)
• Gaps: 52/191 - (27%)

  Fly    46 GGIRSTYQHFGPQ----GGQDSGFPS--PRSALGYPFPPMHQNSYSGYHL--GSYAPPC--ASPP 100
            ||..|.|..|.|:    ||  :|.|:  ..|.|||     :...|...|:  ....|.|  |.||
Human    48 GGASSDYGAFYPRPVAPGG--AGLPAAVSGSRLGY-----NNYFYGQLHVQAAPVGPACCGAVPP 105

  Fly   101 KDDFSISDKCEDSGLRVNGKG---------------------------------KKMRKPRTIYS 132
            ......|  |..:.....|.|                                 ::.|:.|||::
Human   106 LGAQQCS--CVPTPPGYEGPGSVLVSPVPHQMLPYMNVGTLSRTELQLLNQLHCRRKRRHRTIFT 168

  Fly   133 SLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNS 193
            ..||:.|...||.|:|..:..|.:||..:.|.:.:|::||:|||:|:::..:::.....|:
Human   169 DEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQKRSSSEESENA 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	22/55 (40%)
GSC	NP_776248.1	Homeodomain	161..217	CDD:459649	22/55 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	213..257		2/17 (12%)