Protein Alignment Dll and Evx1

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_031992.1
• Gene: Evx1 / 14028
• MGIID: 95461
• Length: 416
• Species: Mus musculus
• Alignment Length: 354
• Identity: 82/354 - (23%)
• Similarity: 115/354 - (32%)
• Gaps: 120/354 - (33%)

  Fly     7 PHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSPRSA 71
            |.|.:...||........|:            ..:|||.|.                   .||||
Mouse    54 PPTSRERGGGGQEEEPVDGL------------AGSAAGLGA-------------------EPRSA 87

  Fly    72 ----LGYPFPPM-HQNSYSGYHLGSYA---------------PPCA----------SPPKDDFSI 106
                || |.||: ..:|.||....|.:               |.||          :|..|....
Mouse    88 GAAMLG-PGPPVPSADSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKAPGSDALGS 151

  Fly   107 SDKCEDSGLRVNG--------------KGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAEL 157
            |........:.||              ...:||:.||.::..|:.:|.:.|.|..|::.|.|.||
Mouse   152 SPTSGSEAPKSNGGSGGSGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCEL 216

  Fly   158 AASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGELANGRF 222
            ||:|.|.:|.:|:||||||.|.|:...|..             .|:|             |:..|
Mouse   217 AAALNLPETTIKVWFQNRRMKDKRQRLAMT-------------WPHP-------------ADPAF 255

  Fly   223 LWAALETNGTLALVHSTGGNNGGGSNSGSPSHYLPPGHSP------TPSSTPVSELSPEFPPTGL 281
            .        |..:.|:..   .||.....|||...|.:||      :.:|...|..|....|...
Mouse   256 Y--------TYMMSHAAA---AGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGPLRPLDT 309

  Fly   282 SPPTQAPWDQKPHWIDHKPPPQMTPQPPH 310
            ......|:.:.......:.|| :.|.|.|
Mouse   310 FRVLSQPYPRPELLCAFRHPP-LYPGPAH 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	25/55 (45%)
Evx1	NP_031992.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..120		22/97 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..178		5/39 (13%)
		Homeodomain	184..240	CDD:459649	25/55 (45%)