Protein Alignment Dll and Dlx2

DIOPT Version :9

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_034184.1
• Gene: Dlx2 / 13392
• MGIID: 94902
• Length: 332
• Species: Mus musculus
• Alignment Length: 380
• Identity: 128/380 - (33%)
• Similarity: 154/380 - (40%)
• Gaps: 153/380 - (40%)

  Fly    15 GGNTAA------------SVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPS 67
            |||:.:            |.|..::....|::...|||.|.|.||..|.|.|.|......||
Mouse    38 GGNSNSSSSNSSLHKPQESPTLPVSTATDSSYYTNQQHPAGGGGGGASPYAHMGSYQYHASG--- 99

  Fly    68 PRSALGYPFPPMHQNSY---SGYHLG------SYAPPCAS-------PPKDDFSISDKCEDSGLR 116
                       ::..||   |.|.||      ||||...|       |.|:|.       :..:|
Mouse   100 -----------LNNVSYSAKSSYDLGYTAAYTSYAPYGTSSSPVNNEPDKEDL-------EPEIR 146

  Fly   117 -VNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYK 180
             ||||.||:|||||||||.||..|.||||:|||||||||||||||||||||||||||||||||:|
Mouse   147 IVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFK 211

  Fly   181 KMMKAA-----QGPGTNSGMP-------------------LGGGGPNPGQHSPNQMHSGELANGR 221
            ||.|:.     |.||.::..|                   :.||||..|
Mouse   212 KMWKSGEIPTEQHPGASASPPCASPPVSAPASWDFGAPQRMAGGGPGSG---------------- 260

  Fly   222 FLWAALETNGTLALVHSTGGNNGGGSNSGSPS--------HYLPPGHSPTPSSTPVSELSPEFPP 278
                              ||  |.||:..|||        :| |..|..:.|::.:...:|
Mouse   261 ------------------GG--GAGSSGSSPSSAASAFLGNY-PWYHQASGSASHLQATAP---- 300

  Fly   279 TGLSPPTQAPWDQKPHWIDHKPPPQMTPQPPHPAATLHPQTHHHNPPPQMGGYVP 333
                             :.|   |..|||..|     |...|||     .||..|
Mouse   301 -----------------LLH---PSQTPQAHH-----HHHHHHH-----AGGGAP 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeobox	127..180	CDD:278475	47/52 (90%)
Dlx2	NP_034184.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..83		12/44 (27%)
		DLL_N	54..135	CDD:289198	27/94 (29%)
		Homeobox	158..211	CDD:278475	47/52 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..272		15/88 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..332		12/32 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843255
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000655
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840