Protein Alignment Dll and Dlx1

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_034183.1
• Gene: Dlx1 / 13390
• MGIID: 94901
• Length: 255
• Species: Mus musculus
• Alignment Length: 304
• Identity: 117/304 - (38%)
• Similarity: 141/304 - (46%)
• Gaps: 87/304 - (28%)

  Fly    18 TAASVTPGINIP--GKSAFVEL----QQHAAA----GYGGIRSTYQ--HFGPQGGQD--SGFPSP 68
            |..::...:|.|  ||:.|:|.    ||.:.:    |:..:...:.  |..|.|...  |.|..|
Mouse     2 TMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASSFSRP 66

  Fly    69 RSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSG-------------LRVNGK 120
               ||||:    .||.|.:....|.....|.|........:.||.|             :|.|||
Mouse    67 ---LGYPY----VNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVRFNGK 124

  Fly   121 GKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKA 185
            |||:|||||||||||||.||||||:|||||||||||||||||||||||||||||:|||:||:||
Mouse   125 GKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMK- 188

  Fly   186 AQGPGTNSGMPLGGGGPNPGQHSPNQMHSGELANGRFLWAALETNGTLALVHSTGGNNGGGSNSG 250
             ||     |..|.|..               |||||.|                        ::|
Mouse   189 -QG-----GAALEGSA---------------LANGRAL------------------------SAG 208

  Fly   251 SPSHYLPPGHSPTPSSTPVSELSPEFPPTGLSPPTQAPWDQKPH 294
            ||.  :|||.:|..||...|..|     .|...|:...|....|
Mouse   209 SPP--VPPGWNPNSSSGKGSGSS-----AGSYVPSYTSWYPSAH 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	51/55 (93%)
Dlx1	NP_034183.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		9/35 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..118		3/22 (14%)
		Homeodomain	129..185	CDD:459649	51/55 (93%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..233		13/59 (22%)