Protein Alignment Dll and Cdx4

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_031700.1
• Gene: Cdx4 / 12592
• MGIID: 88362
• Length: 282
• Species: Mus musculus
• Alignment Length: 280
• Identity: 75/280 - (26%)
• Similarity: 106/280 - (37%)
• Gaps: 106/280 - (37%)

  Fly    20 ASVTPG-INIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSPRS----ALGYP---- 75
            |.:.|| :..||.|        :.||          .|..||  ||.|.|.|    |..||
Mouse    11 AGMYPGTLRSPGGS--------STAG----------VGTSGG--SGSPLPASNFTAAPVYPHYVG 55

  Fly    76 FPPMHQNSYSGYHLGSYAPPCASPPKDDF------------------------------------ 104
            :|.|......|..||:::.| .|||::|:
Mouse    56 YPHMSNMDPHGPSLGAWSSP-YSPPREDWSTYPGPPSTMGTVPMNDMTSPVFGSPDYSTLGPTSG 119

  Fly   105 -----SISDKCE------DSG---------------------LRVNGKGKKMRKPRTIYSSLQLQ 137
                 |:.|...      |||                     ::|.||.:...|.|.:|:..|..
Mouse   120 ASNGGSLPDAASESLVSLDSGTSGATSPSRSRHSPYAWMRKTVQVTGKTRTKEKYRVVYTDHQRL 184

  Fly   138 QLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGP 202
            :|.:.|...:|:.:..::|||.:|||::.||||||||||:|.:||:|.......|:|   |....
Mouse   185 ELEKEFHCNRYITIRRKSELAVNLGLSERQVKIWFQNRRAKERKMIKKKISQFENTG---GSVQS 246

  Fly   203 NPGQHSPNQMHSGELANGRF 222
            :.|..||     |||.|..|
Mouse   247 DSGSISP-----GELPNAFF 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	24/55 (44%)
Cdx4	NP_031700.1	Caudal_act	13..168	CDD:461413	35/175 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	13..36		10/42 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	98..156		5/57 (9%)
		Homeodomain	173..228	CDD:459649	24/54 (44%)