Protein Alignment Dll and Alx3

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_031467.1
• Gene: Alx3 / 11694
• MGIID: 1277097
• Length: 343
• Species: Mus musculus
• Alignment Length: 380
• Identity: 92/380 - (24%)
• Similarity: 132/380 - (34%)
• Gaps: 144/380 - (37%)

  Fly     4 PDAPHTP-------KYMDGGNTAASVTPGINIPG-----KSAFVELQQHAAAGY--------GGI 48
            |..|:.|       ||:.      .:.||..:.|     .||..|.:...||.:        ||.
Mouse    56 PLEPYLPEPAKPPAKYLQ------DLGPGPVLNGGHFYEGSAEAEEKASKAASFPQLPVDCRGGP 114

  Fly    49 RSTYQHFGPQGGQDSGFPSP-RSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCED 112
            |.     ||...|.|  |.| .::|..|..|                          .:.|..|
Mouse   115 RD-----GPSNVQAS--PGPCLASLSVPLSP--------------------------GLPDSME- 145

  Fly   113 SGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRS 177
               ....|.|| |:.||.:|:.||::|.:.||:|.|..:..|.:||....||:.:|::||||||:
Mouse   146 ---LAKTKSKK-RRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRA 206

  Fly   178 KYKK-----MMKAAQGPGTN----SGMPLGGGGPNPGQHSPNQMHSGELANGRFLWAALETNGTL 233
            |::|     .|:..:.|.|.    |.:|.....|             :|.|.  ||.:
Mouse   207 KWRKRERYGKMQEGRNPFTTAYDISVLPRTDSHP-------------QLQNS--LWPS------- 249

  Fly   234 ALVHSTGGNNGGGSNSGSPSHYLPPGHSPTPSSTPVSELSPEFPPTGLSPPTQAPWDQKPHWIDH 298
                         ..||||.       .|...|           |.|:..|..:|:..     .|
Mouse   250 -------------PGSGSPG-------GPCLMS-----------PEGIPSPCMSPYSH-----SH 278

  Fly   299 KPPPQMTPQPPHPAATLHPQTHH-HNPPPQMGGYVPQYWYQPE-----TNPSLVT 347
            .........|..|||  ||..:. |..||.:||:.    ::|.     .:||||:
Mouse   279 GNVAGFMGVPASPAA--HPGIYSIHGFPPALGGHS----FEPSPDGDYKSPSLVS 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	24/55 (44%)
Alx3	NP_031467.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..122		18/76 (24%)
		Homeodomain	154..210	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..343		6/23 (26%)