Protein Alignment Dll and Drgx

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: XP_006518472.1
• Gene: Drgx / 107751
• MGIID: 2148204
• Length: 354
• Species: Mus musculus
• Alignment Length: 325
• Identity: 84/325 - (25%)
• Similarity: 125/325 - (38%)
• Gaps: 87/325 - (26%)

  Fly    28 IPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSPRSALGYPFPPMHQNSYSGYHLGSY 92
            :|.|.  :..:|.||....|  :|::|       .|..|.|  ||..|..|:..::...:|
Mouse    49 VPPKP--IRRRQLAALCQAG--ATHRH-------KSARPLP--ALVQPSGPIRPSAMFYFH---- 96

  Fly    93 APPC--ASPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERA 155
            .||.  .:.|..:.|..| .:|..||     :|.|:.||.::..||:.|...|.:|.|..:..|.
Mouse    97 CPPQLEGTAPFGNHSTGD-FDDGFLR-----RKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTRE 155

  Fly   156 ELAASLGLTQTQVKIWFQNRRSKYKKMMKAA--QGPGTNSGM------PLGG-GGPNPGQHSPNQ 211
            |||..:.||:.:|::||||||:|::|..:.|  |.||....|      |:.. ..|.||..:.::
Mouse   156 ELAMKINLTEARVQVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGDQTRSK 220

  Fly   212 MHSGEL---------ANGRFLWAALETNGTL--------ALVHSTGGNNGGGSNSGSPS----HY 255
            ..:.|.         ..|.|..:.|.  |||        ||.|......|...:...|.    .:
Mouse   221 KEALEAQQSLGRTVGPTGPFFPSCLP--GTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSF 283

  Fly   256 LPP-------------------GHS----------PTPSSTPVSELSPEFPPTGLSPPTQAPWDQ 291
            ||.                   .||          |:.||:| ...|.:.||.|....|....:|
Mouse   284 LPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLPSTSSSP-GPASKQAPPEGSQDKTSPTKEQ 347

  Fly   292  291
            Mouse   348  347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	23/55 (42%)
Drgx	XP_006518472.1	Homeodomain	125..181	CDD:459649	23/55 (42%)
		OAR	292..309	CDD:461067	1/16 (6%)