Protein Alignment Dll and CDX2

DIOPT Version :9

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: XP_011533177.1
• Gene: CDX2 / 1045
• HGNCID: 1806
• Length: 321
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 88/347 - (25%)
• Similarity: 123/347 - (35%)
• Gaps: 137/347 - (39%)

  Fly    10 PKYMD--GGNTAASVTPGINI-----PGKSAFVELQQHAAAGYGG-IRSTYQHFGPQG------- 59
            |:|.|  |.:.||:.....|:     ||.|        ..|.||. :|..:..:.|.|
Human    35 PQYPDYGGYHVAAAAAAAANLDSAQSPGPS--------WPAAYGAPLREDWNGYAPGGAAAAANA 91

  Fly    60 ---GQDSGFPSPRSALGYPFP----PMHQNSYSGYHLGSYAPPCAS----------PPKDDFSIS 107
               |.:.|  ||.:|:||..|    |.|...:..:|..: ||.|||          |.....:.:
Human    92 VAHGLNGG--SPAAAMGYSSPADYHPHHHPHHHPHHPAA-APSCASGLLQTLNPGPPGPAATAAA 153

  Fly   108 DKCEDSGLRVNGKGKKMRKP-------------------------RTIYSSLQLQQLNRRFQRTQ 147
            ::....|.|.| ..:.||||                         |.:|:..|..:|.:.|..::
Human   154 EQLSPGGQRRN-LCEWMRKPAQQSLGSQALTSPSSTVKTRTKDKYRVVYTDHQRLELEKEFHYSR 217

  Fly   148 YLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMK------AAQGPGTNSGMPLGGGGPNPGQ 206
            |:.:..:|||||:|||::.||||||||||:|.:|:.|      ..|.|......|     |.|.|
Human   218 YITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKLQQQQQQQPPQPPPPP-----PQPPQ 277

  Fly   207 HSPNQMHSGELANGRFLWAALETNGTLALVHSTGGNNGGGSNSGSPSHYLPPGHSPTPSSTPVSE 271
            ..|..:.|                                              .|.|.| |||.
Human   278 PQPGPLRS----------------------------------------------VPEPLS-PVSS 295

  Fly   272 LSPEFP--------PTG--LSP 283
            |....|        |||  |:|
Human   296 LQASVPGSVPGVLGPTGGVLNP 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeobox	127..180	CDD:278475	26/77 (34%)
CDX2	XP_011533177.1	Caudal_act	13..171	CDD:282574	37/147 (25%)
		Homeobox	198..250	CDD:278475	25/51 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810