Protein Alignment Dll and Hoxb2

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_598793.2
• Gene: Hoxb2 / 103889
• MGIID: 96183
• Length: 354
• Species: Mus musculus
• Alignment Length: 315
• Identity: 87/315 - (27%)
• Similarity: 116/315 - (36%)
• Gaps: 86/315 - (27%)

  Fly    29 PGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSPRSALGYP-------FPPMHQNSYSG 86
            |.:..|..||..|        ||.|..|.|.....| |:.||....|       ||.|.:...:.
Mouse    48 PLEQTFPSLQLGA--------STLQRPGSQKQAGDG-PALRSPPPLPVAPPAPEFPWMKEKKSTK 103

  Fly    87 YHLGSYAPPCASPPKDDFSISD---KCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQY 148
            ....|.|.|  ||.......|:   ..:..||...| |...|:.||.|::.||.:|.:.|...:|
Mouse   104 KPSQSAASP--SPAASSVRASEVGSPSDGPGLPECG-GSGSRRLRTAYTNTQLLELEKEFHFNKY 165

  Fly   149 LALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGP----------- 202
            |..|.|.|:||.|.||:.|||:||||||.|:|:..:..:.|   .|.|   |||
Mouse   166 LCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPP---EGEP---GGPSAQDDAGEPAE 224

  Fly   203 ----NPGQHSPNQM-----HSGELANGRFLWAALETNGT------LALVHSTGGNNGGGS---NS 249
                :||..:.:::     |..|.|.|        ..|.      ...:.|.|.::.|.:   ..
Mouse   225 EPTVSPGDVATHRLREACFHPAEAAQG--------PRGAPPSALPATTLESVGASSPGCTMLRAG 281

  Fly   250 GSPSHYLPPGHSPTPSSTPVSELSPEFPPT--------------GLSPPTQAPWD 290
            |..|..||....|....:|       |.|.              ||||..|...|
Mouse   282 GRQSEPLPEDACPERQDSP-------FLPDLNFFAADSCLQMSGGLSPSLQGSLD 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	28/55 (51%)
Hoxb2	NP_598793.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..143		28/106 (26%)
		Antp-type hexapeptide	92..97		2/4 (50%)
		Homeodomain	142..198	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..231		9/43 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..295		11/56 (20%)