DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dll and dlx4

DIOPT Version :9

Sequence 1:	NP_001137759.1	Gene:	Dll / 37973	FlyBaseID:	FBgn0000157	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	XP_002935758.3	Gene:	dlx4 / 100494171	XenbaseID:	XB-GENE-876742	Length:	253	Species:	Xenopus tropicalis

Alignment Length:	317	Identity:	106/317 - (33%)
Similarity:	135/317 - (42%)	Gaps:	118/317 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SVTPGINIPGKSAFVEL---------QQHAAA---G----YGGIRSTYQH-FGPQGGQDSGFPS- 67
            |:...:..|.||||:|.         .||:.|   |    :|.:.:.::. |.|      |.||
Frog     3 SIADSLLDPSKSAFLEFSHGPTSSPQSQHSPALAHGHYPLHGFLPTAHEGLFSP------GTPSF 61

  Fly    68 PRSALGYPF-PPMHQNSYSGYHLGS-------YAPPCASPPK----DDFSISDKCEDSGLRVNGK 120
            ....|.||: ...|.:....:|.||       |.....|..:    .:...|...|:..:|:|||
Frog    62 GGRTLPYPYASSSHHHQQQHHHNGSAYLNYQQYTSTIGSSARLHEDQEMEKSTVIENGEIRINGK 126

  Fly   121 GKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKA 185
            |||:|||||||||||||.||:|||:||||||||||||||.||||||||||||||:||||||:||
Frog   127 GKKIRKPRTIYSSLQLQALNQRFQQTQYLALPERAELAAQLGLTQTQVKIWFQNKRSKYKKVMK- 190

  Fly   186 AQGPGTNSGMPLGGGGPNPGQHSPNQMHSGELANGRFLWAALETNGTLALVHSTGGNNGGGSNSG 250
                                       |...:                             .:..
Frog   191 ---------------------------HGSSV-----------------------------QDED 199

  Fly   251 SPSHYLPPGHSPTPSSTPVSELSPEFPP------TGLSPPTQ-------APWDQKPH 294
            .|:           ||:.::..||..||      ||.|.|..       :||.| ||
Frog   200 QPA-----------SSSALTPCSPNMPPLWDIPSTGKSAPLSCNYLNSFSPWYQ-PH 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeobox	127..180	CDD:278475	47/52 (90%)
dlx4	XP_002935758.3	COG5576	98..239	CDD:227863	76/208 (37%)
dlx4	XP_002935758.3	Homeobox	133..187	CDD:395001	48/53 (91%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	109	1.000	Domainoid score	I6276
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	147	1.000	Inparanoid score	I4306
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1416398at2759
OrthoFinder	1	1.000	-	-		FOG0000655
OrthoInspector	1	1.000	-	-		otm47671
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X884
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.060