Protein Alignment Dll and nkx2-1

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: XP_002935383.1
• Gene: nkx2-1 / 100135015
• XenbaseID: XB-GENE-485985
• Length: 346
• Species: Xenopus tropicalis
• Alignment Length: 335
• Identity: 86/335 - (25%)
• Similarity: 119/335 - (35%)
• Gaps: 118/335 - (35%)

  Fly    20 ASVTPGINIPGKSAF-------VELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSPRSALGYPFP 77
            |..:.|:..|..:|:       ..:|||.....|.:.:.| |....|                .|
 Frog    28 AMESAGLGAPLSAAYRQSQVSQASMQQHGMGHNGPVSAAY-HMTAAG----------------VP 75

  Fly    78 PMHQNSYSGY---HLGSYAPPCASPPKDD------------------FSISDKC--EDSGLRVNG 119
            .:...:..||   :||:.......||..|                  ||...:.  ..||:.:.|
 Frog    76 QLSHTTMGGYCNGNLGNLGNMSELPPYQDTMRNSSATGWYGANPDPRFSTISRFMGPSSGMNMGG 140

  Fly   120 ---------KGKKM--------RKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQ 167
                     .||.|        ||.|.::|..|:.:|.|||::.:||:.|||..||:.:.||.||
 Frog   141 LGNMGSLGDVGKSMTPLQATPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQ 205

  Fly   168 VKIWFQNRRSKYKKMM--KAA--------------QGPG-------TNSGMPLGGGGPNPGQHSP 209
            |||||||.|.|.|:..  |||              |.|.       ...|.|...|...|
 Frog   206 VKIWFQNHRYKMKRQAKDKAAQQQMQQDNSSCQQQQSPRRVAVPVLVKDGKPCQAGSNTP----- 265

  Fly   210 NQMHSGELANGRFLWAALETNGTLALVHSTGGNNGGG------SNSGSPSHYLPPGHSPTPSS-- 266
                          .|||:::........|..:||.|      :||...|..|.| ||.:|||
 Frog   266 --------------TAALQSHQQQTATAITVTSNGLGPHQSHQTNSAGQSPDLVP-HSNSPSSLQ 315

  Fly   267 ---TPVSELS 273
               |.:|.|:
 Frog   316 NQVTSLSHLN 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	29/55 (53%)
nkx2-1	XP_002935383.1	Homeodomain	163..219	CDD:459649	29/55 (53%)