Protein Alignment Orc4 and ORC4

DIOPT Version :10

• Sequence 1: NP_477320.1
• Gene: Orc4 / 37970
• FlyBaseID: FBgn0023181
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_015488.1
• Gene: ORC4 / 856291
• SGDID: S000006366
• Length: 529
• Species: Saccharomyces cerevisiae
• Alignment Length: 419
• Identity: 111/419 - (26%)
• Similarity: 189/419 - (45%)
• Gaps: 83/419 - (19%)

  Fly     3 EADRELVSIRRFLKERLQRDYTTLR-------GYAKE-RSNVRLLLQRTAEMGESNSLLLLGPRG 59
            ::|....|::|.|   ||:.|.||.       .|.:: :..:..:::::....||:|::|:|||.
Yeast    44 DSDPGFGSLQRRL---LQQLYGTLPTDEKIIFTYLQDCQQEIDRIIKQSIIQKESHSVILVGPRQ 105

  Fly    60 SGKTTLINSVLADLLPNKSFGENTLIVHLDGNLHTDDRVALKSITVQMQ---------------- 108
            |.||.|::..|:  |..:|:.|..:.:.|:|.:|: ::.|:..|..|::
Yeast   106 SYKTYLLDYELS--LLQQSYKEQFITIRLNGFIHS-EQTAINGIATQLEQQLQKIHGSEEKIDDT 167

  Fly   109 -LENAADGKVFGSFAENLAFLLQCLKAGGKHSK----------SVIFILEEFDLFCAHHNQTLLY 162
             ||..:.|.:...|.:.|..|....|...:.|.          :|:||.:|.|.|.....|||||
Yeast   168 SLETISSGSLTEVFEKILLLLDSTTKTRNEDSGEVDRESITKITVVFIFDEIDTFAGPVRQTLLY 232

  Fly   163 NLFDVSQSAQAPICVLGVTCRLDVIELLEKRVKSRFSHRQVFLFPSLRRFEDYVDLCRDLLSLPT 227
            ||||:.:.::.|:|:.|.|.:|:::|.||||||||||.|.::: |.::..:|.||..|:||::
Yeast   233 NLFDMVEHSRVPVCIFGCTTKLNILEYLEKRVKSRFSQRVIYM-PQIQNLDDMVDAVRNLLTV-- 294

  Fly   228 GNSLLLAAEKIYNLQNIQSGALYFSRNHFDPGEYGFSPRLRDAWNKQICKVLATQQARSTLQALH 292
                                     |:...|..        ..||:.:.|.|:..::........
Yeast   295 -------------------------RSEISPWV--------SQWNETLEKELSDPRSNLNRHIRM 326

  Fly   293 DFDI--SEAYLKNFLFRLVAHLRPQSPHITAEKMAAVGSQFEGDDKIELLCG----LSVLELCLI 351
            :|:.  |...|||.:..|||..:......||.|..:....:..:.....|.|    ||.|||.::
Yeast   327 NFETFRSLPTLKNSIIPLVATSKNFGSLCTAIKSCSFLDIYNKNQLSNNLTGRLQSLSDLELAIL 391

  Fly   352 IAIKHHSQIYDRDSFNFEIIYARFSKFAK 380
            |:....:......||||.:.||.:.|..|
Yeast   392 ISAARVALRAKDGSFNFNLAYAEYEKMIK 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orc4	NP_477320.1	CDC6	42..>207	CDD:441083	61/191 (32%)
		ORC4_C	217..440	CDD:464223	37/170 (22%)
ORC4	NP_015488.1	CDC6	81..>276	CDD:441083	61/198 (31%)
		ORC4_C	286..517	CDD:464223	37/170 (22%)