Protein Alignment Orc4 and orc4

DIOPT Version :9

• Sequence 1: NP_477320.1
• Gene: Orc4 / 37970
• FlyBaseID: FBgn0023181
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_595825.1
• Gene: orc4 / 2541298
• PomBaseID: SPBP23A10.13
• Length: 972
• Species: Schizosaccharomyces pombe
• Alignment Length: 490
• Identity: 140/490 - (28%)
• Similarity: 239/490 - (48%)
• Gaps: 89/490 - (18%)

  Fly     3 EADRELVSIRRFLKERL-QRDYTTLRGYAKERSNVRLLLQRTAEMGESNSLLLLGPRGSGKTTLI 66
            |.|.:|.:|:..:..|| .:.:..|.|:..|::.:...:::|..:||.||::::|||||||:.|:
pombe   528 EIDSQLHTIKSTIAARLCGKSHIPLVGHMDEQTKLYQWVRQTIVLGEGNSVIIVGPRGSGKSVLV 592

  Fly    67 NSVLADLLPNKSFGENTLIVHLDGNLHTDDRVALKSITVQM--QLENAADGKVFGS---FAENLA 126
            :.:|:...  :...|.:.:|.|:|...|||::||:.|:.|:  :||:....:...|   |::.|.
pombe   593 DDILSRAA--QEINEKSYVVRLNGTYQTDDKLALREISRQLSIELESIESDEALKSEMNFSDTLT 655

  Fly   127 FLLQCLKAGGKH-------------SKSVIFILEEFDLFCAHHNQTLLYNLFDVSQSAQAPICVL 178
            .||..|    .|             |.:|||:|||||||..|..|.|||||||::||.:|||.::
pombe   656 KLLATL----SHPVDLGIAEDVMTTSAAVIFVLEEFDLFVQHSRQMLLYNLFDIAQSRKAPILII 716

  Fly   179 GVTCRLDVIELLEKRVKSRFSHRQVFLFP--SLRRFEDYVDLCRDLLSLPTGNSLLLAAEKIYNL 241
            |:|.|.|..|.|||||||||||..:.:.|  ||..||
pombe   717 GLTTRYDCSESLEKRVKSRFSHMVIPMRPPSSLSEFE---------------------------- 753

  Fly   242 QNIQSGALYFSRNHFDPGEYGFSPRLRDAWNKQICKVLATQQARSTLQAL---HDF---DISEAY 300
             .|....||.|       :.|...::...||:::.::|:  ..||.|..|   |.|   ::...|
pombe   754 -QILKSVLYVS-------DEGGKDQIITCWNQRVDELLS--DTRSHLHKLVQHHYFASRNLKLLY 808

  Fly   301 LKNFLFRLVAHLRPQSPHITAEKMAAVGSQFEGDDKIELLCGLSVLELCLII-AIKHHSQIYDRD 364
            : :.||.::: :.|..|.:..|..|.:..:. .|.|:||:..||:|||.|:| |::..::  |..
pombe   809 V-DLLFPILS-MAPDRPLLADEDFANISLKV-SDHKVELVKNLSLLELALLICAVRFEAR--DIP 868

  Fly   365 SFNFEIIYARFSKFAKVSTTMQAVE-----------RSIVLKAFEHLRIAELIMPLTGGAGGGVG 418
            :.||...|..:.:..:.|....|..           |.:.|:|:|.|....||:|:....... |
pombe   869 ACNFNSAYQEYRQLHQSSVINAAASGALAHSSRLWGRDVALEAWETLGSIGLIIPVHPSTNVS-G 932

  Fly   419 KVQKEFEMHKLALTYSQIHHCMQRYQALPTEVAQW 453
            .:.::.::.:..:..:.:...::.::.||:...:|
pombe   933 ALSRQCQLWQPEVDINVVSVGLREHRRLPSHYYRW 967

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orc4	NP_477320.1	AAA_16	39..178	CDD:289934	59/156 (38%)
		AAA	50..205	CDD:214640	72/172 (42%)
		ORC4_C	257..430	CDD:291303	44/190 (23%)
orc4	NP_595825.1	AAA_16	551..716	CDD:289934	62/170 (36%)
		AAA	575..741	CDD:214640	72/171 (42%)
		ORC4_C	754..944	CDD:291303	48/204 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	99	1.000	Domainoid score	I1839
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8059
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005811
OrthoInspector	1	1.000	-	-		oto100680
orthoMCL	1	0.900	-	-		OOG6_103029
Panther	1	1.100	-	-	LDO	PTHR12087
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R873
SonicParanoid	1	1.000	-	-		X4202
TreeFam	0	0.000	Not matched by this tool.
	10	9.940