Protein Alignment key and IKBKG

DIOPT Version :9

• Sequence 1: NP_001246503.1
• Gene: key / 37967
• FlyBaseID: FBgn0041205
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_001093326.2
• Gene: IKBKG / 8517
• HGNCID: 5961
• Length: 487
• Species: Homo sapiens
• Alignment Length: 398
• Identity: 93/398 - (23%)
• Similarity: 141/398 - (35%)
• Gaps: 130/398 - (32%)

  Fly   101 LCSLQGSAEEVVKLQNMMTEYLALKSTLDKVNQTM------------------------------ 135
            |.|.||:.|   .||..:.|...|:..:.:.||.:
Human   109 LPSEQGAPE---TLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARK 170

  Fly   136 ----LNYHNLTQQWRQEAADREHQYKEHVKECQ-----------AQIAILRVENQELKRDLETKI 185
                |....|..:.::|.|.||   .||:|.||           ||:..|..|.||.:..||...
Human   171 LVERLGLEKLDLKRQKEQALRE---VEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAAT 232

  Fly   186 EQIEGVHTIRLKEQDELRKSVSEKQSLIDNMRVEIDKLKQLNHSFEFVPEYATESKSQELIKKMQ 250
            ::.:.:........::.|:..||:::|.....|::|:|:....|.|.......::.|:|..|..|
Human   233 KECQALEGRARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQ 297

  Fly   251 LDI----------NELKA--------RDIQ-----------------KQEVIKG----------- 269
            |.:          |.:|:        |.:|                 |||||..
Human   298 LQVAYHQLFQEYDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIV 362

  Fly   270 ------LQIQNDIYRRDFEMERADREKNAGEKDQYLMDLRSLQRRNQELIEALAESHKASKACST 328
                  |:.|.|||:.||:.||..|||.|.:|:.....|..|||...:|        |||  |..
Human   363 METVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKL--------KAS--CQE 417

  Fly   329 ASPLSSSRS-NLREEQRPVRILDPTGA---------SSRTS----DTTLRCPICSKSFNALSVLQ 379
            ::.:...|. ::...|.|   |.|..|         |.|.|    .....||.|......:..||
Human   418 SARIEDMRKRHVEVSQAP---LPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQAPDMDTLQ 479

  Fly   380 SHVNDCLD 387
            .||.:|::
Human   480 IHVMECIE 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
key	NP_001246503.1	DUF499	<168..>351	CDD:303008	56/235 (24%)
		UBAN	230..313	CDD:197361	33/134 (25%)
IKBKG	NP_001093326.2	NEMO	112..179	CDD:288434	10/69 (14%)
		CC2-LZ	327..412	CDD:293124	25/92 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326045at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920