Protein Alignment key and Ikbkg

DIOPT Version :9

• Sequence 1: NP_001246503.1
• Gene: key / 37967
• FlyBaseID: FBgn0041205
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_001129539.1
• Gene: Ikbkg / 16151
• MGIID: 1338074
• Length: 430
• Species: Mus musculus
• Alignment Length: 463
• Identity: 104/463 - (22%)
• Similarity: 175/463 - (37%)
• Gaps: 142/463 - (30%)

  Fly    29 CGNAQEAKETVASTSTQPPTVNCIPVSITASQQQHKSLDSGSSQQQSLATSFIMGEIQSDVLKNS 93
            |.:.|:. :|::....:.|..|.:...:..|        .|.::.|.:     :|| :|.:.|.:
Mouse     6 CCDDQDT-QTLSCWMNKHPWKNQLSEMVQPS--------GGPAEDQDM-----LGE-ESSLGKPA 55

  Fly    94 VYSQFPSLCSLQGSAEEVVKLQNMMTEYLALKSTLDKVNQTM------LNYHNLTQQWRQE---- 148
            :.    .|.|.||:.|   .||..:.|...|:..:.:.||.:      |.:..::|:..:|
Mouse    56 ML----HLPSEQGTPE---TLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMC 113

  Fly   149 -------------------AADREHQYK--EHVKECQ-----------AQIAILRVENQELKRDL 181
                               .:.||...|  |.:|:||           ||:..|..|.||.:..|
Mouse   114 KFQEARKLVERLSLEKLDLRSQREQALKELEQLKKCQQQMAEDKASVKAQVTSLLGELQESQSRL 178

  Fly   182 E--TKIEQ-IEGVHTIRLKE-QDELRKSVSEKQSLIDNMRVEIDKLKQLNHSFEFVPEYATESKS 242
            |  ||..| :||    |::. .:::|:..||::.|.....|::|:|:..|.|.|.......::.|
Mouse   179 EAATKDRQALEG----RIRAVSEQVRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAAS 239

  Fly   243 QE-------------------------------------------LIKKMQLDINELKARDIQKQ 264
            :|                                           |:.|.:| |::||....|.:
Mouse   240 EEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQEL-IDKLKEEAEQHK 303

  Fly   265 ---EVIKGLQIQNDIYRRDFEMERADREKNAGEKDQYLMD-LRSLQRRNQELIEALAESHKASKA 325
               |.:..|:.|.|||:.||:.||..|||.. ||.:||.: |..|||          |.:|....
Mouse   304 IVMETVPVLKAQADIYKADFQAERHAREKLV-EKKEYLQEQLEQLQR----------EFNKLKVG 357

  Fly   326 CSTASPLSSSRSNLREEQRPVRILDPTGASSRTSDTTLR-----------CPICSKSFNALSVLQ 379
            |..::.:...|....|..:|..:..|...|...:.:..|           ||.|......:..||
Mouse   358 CHESARIEDMRKRHVETPQPPLLPAPAHHSFHLALSNQRRSPPEEPPDFCCPKCQYQAPDMDTLQ 422

  Fly   380 SHVNDCLD 387
            .||.:|::
Mouse   423 IHVMECIE 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
key	NP_001246503.1	DUF499	<168..>351	CDD:303008	58/233 (25%)
		UBAN	230..313	CDD:197361	31/129 (24%)
Ikbkg	NP_001129539.1	NEMO	62..128	CDD:371612	12/68 (18%)
		SMC_prok_B	<67..>303	CDD:274008	50/243 (21%)
		UBAN	269..355	CDD:197361	30/97 (31%)
		zf_C2H2_10	404..429	CDD:375840	7/24 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	68	1.000	Inparanoid score	I5326
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.920