Protein Alignment key and Ikbkg

DIOPT Version :10

• Sequence 1: NP_001246503.1
• Gene: key / 37967
• FlyBaseID: FBgn0041205
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_001129539.1
• Gene: Ikbkg / 16151
• MGIID: 1338074
• Length: 430
• Species: Mus musculus
• Alignment Length: 463
• Identity: 104/463 - (22%)
• Similarity: 175/463 - (37%)
• Gaps: 142/463 - (30%)

  Fly    29 CGNAQEAKETVASTSTQPPTVNCIPVSITASQQQHKSLDSGSSQQQSLATSFIMGEIQSDVLKNS 93
            |.:.|:. :|::....:.|..|.:...:..|        .|.::.|.:     :|| :|.:.|.:
Mouse     6 CCDDQDT-QTLSCWMNKHPWKNQLSEMVQPS--------GGPAEDQDM-----LGE-ESSLGKPA 55

  Fly    94 VYSQFPSLCSLQGSAEEVVKLQNMMTEYLALKSTLDKVNQTM------LNYHNLTQQWRQE---- 148
            :.    .|.|.||:.|   .||..:.|...|:..:.:.||.:      |.:..::|:..:|
Mouse    56 ML----HLPSEQGTPE---TLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMC 113

  Fly   149 -------------------AADREHQYK--EHVKECQ-----------AQIAILRVENQELKRDL 181
                               .:.||...|  |.:|:||           ||:..|..|.||.:..|
Mouse   114 KFQEARKLVERLSLEKLDLRSQREQALKELEQLKKCQQQMAEDKASVKAQVTSLLGELQESQSRL 178

  Fly   182 E--TKIEQ-IEGVHTIRLKE-QDELRKSVSEKQSLIDNMRVEIDKLKQLNHSFEFVPEYATESKS 242
            |  ||..| :||    |::. .:::|:..||::.|.....|::|:|:..|.|.|.......::.|
Mouse   179 EAATKDRQALEG----RIRAVSEQVRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAAS 239

  Fly   243 QE-------------------------------------------LIKKMQLDINELKARDIQKQ 264
            :|                                           |:.|.:| |::||....|.:
Mouse   240 EEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQEL-IDKLKEEAEQHK 303

  Fly   265 ---EVIKGLQIQNDIYRRDFEMERADREKNAGEKDQYLMD-LRSLQRRNQELIEALAESHKASKA 325
               |.:..|:.|.|||:.||:.||..|||.. ||.:||.: |..|||          |.:|....
Mouse   304 IVMETVPVLKAQADIYKADFQAERHAREKLV-EKKEYLQEQLEQLQR----------EFNKLKVG 357

  Fly   326 CSTASPLSSSRSNLREEQRPVRILDPTGASSRTSDTTLR-----------CPICSKSFNALSVLQ 379
            |..::.:...|....|..:|..:..|...|...:.:..|           ||.|......:..||
Mouse   358 CHESARIEDMRKRHVETPQPPLLPAPAHHSFHLALSNQRRSPPEEPPDFCCPKCQYQAPDMDTLQ 422

  Fly   380 SHVNDCLD 387
            .||.:|::
Mouse   423 IHVMECIE 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
key	NP_001246503.1	Smc	<120..>318	CDD:440809	68/290 (23%)
		UBAN	230..313	CDD:197361	31/129 (24%)
Ikbkg	NP_001129539.1	NEMO	62..128	CDD:431942	12/68 (18%)
		SMC_prok_B	<105..>356	CDD:274008	64/266 (24%)
		UBAN	269..355	CDD:197361	30/97 (31%)
		zf_C2H2_10	404..429	CDD:436483	7/24 (29%)