Protein Alignment CG3589 and Htra1

DIOPT Version :10

• Sequence 1: NP_611968.1
• Gene: CG3589 / 37966
• FlyBaseID: FBgn0035065
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_113909.1
• Gene: Htra1 / 65164
• RGDID: 69235
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 316
• Identity: 69/316 - (21%)
• Similarity: 117/316 - (37%)
• Gaps: 86/316 - (27%)

  Fly   214 CLFAISNALPLGCEGSAVFNNKLRLVGIVICTSFQ-------RHHENV-NLTLAANFGYLLR--- 267
            |...:...:|.|...||....:.: .|:.:|.|.:       :.:.|: .|..|:.....||
  Rat    83 CGEGLQCVVPFGVPASATVRRRAQ-AGLCVCASSEPVCGSDAKTYTNLCQLRAASRRSEKLRQPP 146

  Fly   268 -----------------------NF----MEQLGMSTTAFQLSRE-PSSFAWERTIVVIESAGQQ 304
                                   ||    :|::..:....:|.|: |.|   :|.:.|...:|
  Rat   147 VIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIAPAVVHIELYRKLPFS---KREVPVASGSG-- 206

  Fly   305 GTGTFIRVHNKRFILTCAHVVGQ----NIETVNCRAADREFQSEVIWCNPDSDKPFDLALLTAPQ 365
                || |.....|:|.||||..    .:|..|....:.:.:        |.|:..|:||:....
  Rat   207 ----FI-VSEDGLIVTNAHVVTNKNRVKVELKNGATYEAKIK--------DVDEKADIALIKIDH 258

  Fly   366 D--VPEQCCVRLAR-SPATVGQMVYNAGFPYYVNFSFRHDFNPSIFQ-----GRVI---KCDTGA 419
            .  :|   .:.|.| |....|:.|...|.|    ||.::.....|..     |:.:   ..|...
  Rat   259 QGKLP---VLLLGRSSELRPGEFVVAIGSP----FSLQNTVTTGIVSTTQRGGKELGLRNSDMDY 316

  Fly   420 IMSDGSVQAGQSGGPMFDQNGCILGVCVSNIKLDDVVYPNINTAIPICDIRNTLQQ 475
            |.:|..:..|.||||:.:.:|.::|  ::.:|    |...|:.|||...|:..|.:
  Rat   317 IQTDAIINYGNSGGPLVNLDGEVIG--INTLK----VTAGISFAIPSDKIKKFLTE 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3589	NP_611968.1	Trypsin_2	305..445	CDD:433149	37/154 (24%)
Htra1	NP_113909.1	IGFBP	37..89	CDD:459717	1/5 (20%)
		KAZAL	115..155	CDD:197624	5/39 (13%)
		DegQ	202..477	CDD:440035	47/193 (24%)
		Serine protease. /evidence=ECO:0000250	204..364		46/187 (25%)