Protein Alignment TyrRS-m and MSY1

DIOPT Version :10

• Sequence 1: NP_611967.1
• Gene: TyrRS-m / 37965
• FlyBaseID: FBgn0035064
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: NP_015228.1
• Gene: MSY1 / 856007
• SGDID: S000006018
• Length: 492
• Species: Saccharomyces cerevisiae
• Alignment Length: 483
• Identity: 166/483 - (34%)
• Similarity: 276/483 - (57%)
• Gaps: 47/483 - (9%)

  Fly     2 LPLRRSLLKPLQDVLRHSHRQMSQKNLLELTDRGFFHGIFPDTAAPRMKQLFTRGQQSIYAGFDP 66
            ||..|...:|....::.:....|...|.||..||....:....:..|.| |....:..:|.|.||
Yeast    31 LPKSRFYSQPSALEVQGTSDSRSDNILDELKQRGLVSQVSQPESFLRTK-LNGNDKIKLYCGVDP 94

  Fly    67 TADSLHVGNLLVIMGLIHCQRAGHRPIALVGGATGLIGDPSGRKTERNQLGETVIETNLKAIEQQ 131
            ||.|||:|||:.:|.|:|....||..:.::|||||.:||||||||||:.:...:.::|:.:|.||
Yeast    95 TAQSLHLGNLVPLMVLLHFYVKGHDIVTVIGGATGKVGDPSGRKTERDVMENDIRQSNVASISQQ 159

  Fly   132 LRRVFEN-----HENCLWDSKKQKLPLAPLIIVNNADWYADLQLIDFVANMGRHFRMGSMLSRSS 191
            |:|.|:|     ...|   :..:.:|.......||.:|:.|::::||:|:.|||.|:.|||:|.|
Yeast   160 LQRFFKNGLEYYRNRC---ALTEDVPSGKYTPRNNFNWWKDIKMLDFLADFGRHIRVQSMLARDS 221

  Fly   192 VQSRLESEDGMSFTEFTYQIFQAYDWLHLLRRHNCCFQMGGSDQTGNLMTGHELISRVE---RKR 253
            :.|||::::|:.|.|||||:.||||:.||.:..|...|:||:||.||:..|.:||:|::   .|.
Yeast   222 ISSRLQTKNGLGFNEFTYQVLQAYDFYHLYKEENVTIQVGGNDQWGNITAGIDLINRIQPIKNKG 286

  Fly   254 EVFGLTLPLVTTEEGDKFGKSAGNAVWLDGNKTSPFALYQFFLRMPDSEVEKLLKLFTFIPLPQV 318
            ..||:|:||:||..|:||||||||||::|.:..:.:.:||||....|::|.|.||:|||:...::
Yeast   287 LPFGITVPLLTTATGEKFGKSAGNAVFIDPSINTAYDVYQFFYNTLDADVPKFLKIFTFLNSSEI 351

  Fly   319 EQLMREHTKEPEKRKAQTLLAEDVTLLVHGESGLKQAERVTNALYKGNVEGLAELNLSEIQQTFQ 383
            ::::..|.|.|..|..|||||::||.:::|......:|.::|.:: |..:|           |..
Yeast   352 KKIVETHIKSPSLRYGQTLLAKEVTDMLYGVGSGSDSEALSNIIF-GRYDG-----------TLS 404

  Fly   384 GATMVNL--------LTEPGMSILELAMK-AKCFPTETDAVRIINAGGFYVNQKR------VQNI 433
            .|.:|:|        ..:..:.:::|..| ..|  :.::|.|.::.|..|::..:      :.|:
Yeast   405 AAKLVDLCKKARILQYADREIDLIKLICKLVNC--SVSEARRKLSQGSVYLHHSKSKVNENISNL 467

  Fly   434 AEVLTTGVHILRNGISLLRVGKRNFYIV 461
            |..|      :.:.:.:||:||:..:|:
Yeast   468 APFL------IDDRVLILRIGKQKCFII 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRS-m	NP_611967.1	TyrS	28..464	CDD:439932	161/457 (35%)
MSY1	NP_015228.1	tyrS	54..471	CDD:272976	155/434 (36%)