Protein Alignment TyrRS-m and Yars2

DIOPT Version :10

• Sequence 1: NP_611967.1
• Gene: TyrRS-m / 37965
• FlyBaseID: FBgn0035064
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: NP_001009627.1
• Gene: Yars2 / 287924
• RGDID: 1311696
• Length: 471
• Species: Rattus norvegicus
• Alignment Length: 435
• Identity: 210/435 - (48%)
• Similarity: 291/435 - (66%)
• Gaps: 10/435 - (2%)

  Fly    34 RGFFHGIFPDTAA-PRMKQLFTR----GQQSIYAGFDPTADSLHVGNLLVIMGLIHCQRAGHRPI 93
            ||.|...||::.. ..:.:||.|    ..|::|.|||||.||||||:||.::||.|.|||||..|
  Rat    39 RGLFKEFFPESGTKTELPELFDRRRAGSPQTVYCGFDPTGDSLHVGHLLTLLGLFHFQRAGHNVI 103

  Fly    94 ALVGGATGLIGDPSGRKTERNQLGETVIETNLKAIEQQLRRVFENHENCLWDSKKQKLPLAPLII 158
            |||||:|.|:||||||..||..|....:..|.:|:::.|..:..||.....|.:    |.....:
  Rat   104 ALVGGSTALLGDPSGRTKEREALSAECVRANARALQRGLETLAANHARLFADGR----PWGTFTV 164

  Fly   159 VNNADWYADLQLIDFVANMGRHFRMGSMLSRSSVQSRLESEDGMSFTEFTYQIFQAYDWLHLLRR 223
            ::||.|:....|:||:|.:|.|||||::|||.||||||:|.:|||..||.||:.||||:.:|.|.
  Rat   165 LDNAAWFQKQHLMDFLATVGGHFRMGTLLSRLSVQSRLKSPEGMSLAEFFYQVLQAYDFYYLFRH 229

  Fly   224 HNCCFQMGGSDQTGNLMTGHELISRVERKREVFGLTLPLVTTEEGDKFGKSAGNAVWLDGNKTSP 288
            :.|..|:|||||.||:|:|:|.|.::..: :|||:|:||:|:..|.|.||||||||||:..||||
  Rat   230 YGCRVQLGGSDQLGNIMSGYEFIHKLTGE-DVFGITVPLITSTTGAKLGKSAGNAVWLNREKTSP 293

  Fly   289 FALYQFFLRMPDSEVEKLLKLFTFIPLPQVEQLMREHTKEPEKRKAQTLLAEDVTLLVHGESGLK 353
            |.|||||:|..|..||:.||||||:|||:::.:|:.|.||||||.||..||.:||.||||:.||.
  Rat   294 FELYQFFIRQQDDSVERYLKLFTFLPLPEIDHIMQLHVKEPEKRIAQKRLAAEVTKLVHGQEGLD 358

  Fly   354 QAERVTNALYKGNVEGLAELNLSEIQQTFQGATMVNLLTEPGMSILELAMKAKCFPTETDAVRII 418
            .|:|.|.|||..::|.|..::..|:::.|:.|:...|:.:||.|:::...||...|......|:|
  Rat   359 SAKRCTQALYHSSIEALEVMSDQELKELFKEASFSELVLDPGTSVIDTCRKANAIPDGPRGYRMI 423

  Fly   419 NAGGFYVNQKRVQNIAEVLTTGVHILRNGISLLRVGKRNFYIVRW 463
            ..||..:|.::|.|...||..|.|||:||:|||::|||||||::|
  Rat   424 TEGGVSINHRQVTNPESVLVIGQHILKNGLSLLKIGKRNFYIIKW 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRS-m	NP_611967.1	TyrS	28..464	CDD:439932	210/435 (48%)
Yars2	NP_001009627.1	TyrS	51..468	CDD:439932	204/421 (48%)
		'HIGH' region	76..85		7/8 (88%)
		'KMSKS' region	275..279		2/3 (67%)