Protein Alignment CG3594 and HNRNPDL

DIOPT Version :10

• Sequence 1: NP_523855.1
• Gene: CG3594 / 37964
• FlyBaseID: FBgn0035063
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_112740.1
• Gene: HNRNPDL / 9987
• HGNCID: 5037
• Length: 420
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 44/202 - (21%)
• Similarity: 83/202 - (41%)
• Gaps: 45/202 - (22%)

  Fly    57 PSDPEDSKSEDEAKSDDEAAAEGSAASGAEEEESAENGQITSDQLSSLLRGASKTNRHVLYVTNL 121
            |:|...:..:....|:.|..||||..:.::.::  ::|:                    :::..|
Human   113 PADSSVTMEDMNEYSNIEEFAEGSKINASKNQQ--DDGK--------------------MFIGGL 155

  Fly   122 NFETTKDDLELHFSAAG-----TVKSIRIPKKRRGGFAFVEMADLSSFQNAFQLHNTELQGRNIK 181
            :::|:|.||..:.|..|     |:|:..:..:.| ||.||...|.:|.....:|...:|.|:.|.
Human   156 SWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSR-GFGFVLFKDAASVDKVLELKEHKLDGKLID 219

  Fly   182 VQISEAGKKKSANKK------------NIIKQKNRKLAEMRN-----EQKTFTKSGKFYDKDLKK 229
            .:.::|.|.|...||            ..||:......|:.|     :.||..:.|..:.....:
Human   220 PKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDE 284

  Fly   230 EKAKEML 236
            |..|::|
Human   285 EPVKKLL 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3594	NP_523855.1	SF-CC1	36..>197	CDD:273721	34/156 (22%)
		RRM	116..187	CDD:440488	20/75 (27%)
HNRNPDL	NP_112740.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..83
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	96..120		2/6 (33%)
		RRM1_hnRPDL	149..224	CDD:410152	20/95 (21%)
		RRM2_hnRPDL	234..308	CDD:409998	11/58 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..348
		Necessary for interaction with TNPO1. /evidence=ECO:0000269|PubMed:9524220	342..420
		Necessary for its nuclear import and export	396..420
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	398..420