Protein Alignment CG3594 and SAFB2

DIOPT Version :10

• Sequence 1: NP_523855.1
• Gene: CG3594 / 37964
• FlyBaseID: FBgn0035063
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_055464.1
• Gene: SAFB2 / 9667
• HGNCID: 21605
• Length: 953
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 63/212 - (29%)
• Similarity: 93/212 - (43%)
• Gaps: 39/212 - (18%)

  Fly    57 PSDPE--DSKSEDEAKSDDEAA-------AEGSAASGAEE-----EESAENGQITSDQLSSLLRG 107
            || ||  ||| ||..|.|.:|.       .|.|.:.||::     :|..:...|..|:...:..|
Human   342 PS-PEARDSK-EDGRKFDFDACNEVPPAPKESSTSEGADQKMSSFKEEKDIKPIIKDEKGRVGSG 404

  Fly   108 ASKTNRHVLYVTNLNFETTKDDLELHFSAAG------TVKSIRIPKKRRGGFAFVEMADLSSFQN 166
            :.:.    |:|:.|:..|...||:..||..|      .|.:.|.|..|..||..:..:| .:.:.
Human   405 SGRN----LWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSD-EATKC 464

  Fly   167 AFQLHNTELQGRNIKVQISEAGKKKSANKKNIIKQKNRKLAEMRNEQKTFTKSGKFYDKDLKKEK 231
            ...||.|||.||.|.|   |..|.:.|.|    |..:||..|::.|:  .:...:.:..::|.||
Human   465 ISHLHRTELHGRMISV---EKAKNEPAGK----KLSDRKECEVKKEK--LSSVDRHHSVEIKIEK 520

  Fly   232 A---KEMLARKRWRKKP 245
            .   ||....|:..|||
Human   521 TVIKKEEKIEKKEEKKP 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3594	NP_523855.1	SF-CC1	36..>197	CDD:273721	49/159 (31%)
		RRM	116..187	CDD:440488	25/76 (33%)
SAFB2	NP_055464.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		SAP	30..64	CDD:128789
		PLN03124	31..>153	CDD:215591
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..114
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..404		19/63 (30%)
		RRM_SAFB1_SAFB2	406..481	CDD:410080	25/82 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	525..665		6/13 (46%)
		Interaction with SAFB1	600..953
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	684..953
		Nuclear localization signal. /evidence=ECO:0000255	713..730
		RcnB	756..>843	CDD:444206