DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3594 and MRD1

DIOPT Version :9

Sequence 1:	NP_523855.1	Gene:	CG3594 / 37964	FlyBaseID:	FBgn0035063	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_015437.1	Gene:	MRD1 / 856228	SGDID:	S000006316	Length:	887	Species:	Saccharomyces cerevisiae

Alignment Length:	207	Identity:	56/207 - (27%)
Similarity:	93/207 - (44%)	Gaps:	28/207 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 TVNDDSADLLGNFDDQKRREIFEGTYVDKEDGRNPSDPEDSKSED------EAKSDDEAAAEGSA 81
            |.|.:..|         |.::|.| :|..:....|......|:..      |.::.::|.|..:|
Yeast   674 TTNQNLTD---------RFKVFTG-FVVAQVKTKPDPKHQGKTLSMGFGFVEFRTKEQANAVIAA 728

  Fly    82 ASGAEEEESAENGQITSDQLSSLLRGASKTNRH--VLYVTNLNFETTKDDLELHFSAAGTVKSIR 144
            ..|...:......:::..|.|......:|:|:.  .:.|.||.||.|:.|:...|::.|.:||:|
Yeast   729 MDGTVIDGHKIQLKLSHRQASQSGNTKTKSNKKSGKIIVKNLPFEATRKDVFELFNSFGQLKSVR 793

  Fly   145 IPK---KRRGGFAFVEMADLSSFQNAF-QLHNTELQGRNIKVQISE-----AGKKKSANKKNIIK 200
            :||   |...||||||.......:||. |||...|.||.:.:|.:|     |.::.:...|.:.|
Yeast   794 VPKKFDKSARGFAFVEFLLPKEAENAMDQLHGVHLLGRRLVMQYAEEDAVDAEEEIARMTKKVRK 858

  Fly   201 Q-KNRKLAEMRN 211
            | ...::|.:||
Yeast   859 QVATNEMAALRN 870

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3594	NP_523855.1	RRM3_Prp24	114..184	CDD:240744	29/75 (39%)
MRD1	NP_015437.1	RRM4_MRD1	663..746	CDD:409758	14/81 (17%)
		RRM5_MRD1	763..837	CDD:241014	29/73 (40%)
		RRM1_RBM19_MRD1	2..92	CDD:409754
		RRM	222..612	CDD:223796
		RRM2_MRD1	343..421	CDD:409982
		RRM3_MRD1	532..603	CDD:241012
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0110
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810