Protein Alignment CG3594 and SNRNP70

DIOPT Version :10

• Sequence 1: NP_523855.1
• Gene: CG3594 / 37964
• FlyBaseID: FBgn0035063
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_003080.2
• Gene: SNRNP70 / 6625
• HGNCID: 11150
• Length: 437
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 46/276 - (16%)
• Similarity: 89/276 - (32%)
• Gaps: 100/276 - (36%)

  Fly    55 RNPSDPEDSKSEDEAKSDDEAAAEGSAASGAEEEESAENGQITSDQLSSLLR------------G 107
            |...||.|:.....|::.:|..          |.:..|..:....::.:.|:            .
Human    46 REFEDPRDAPPPTRAETREERM----------ERKRREKIERRQQEVETELKMWDPHNDPNAQGD 100

  Fly   108 ASKTNRHVLYVTNLNFETTKDDLELHFSAAGTVKSIR-IPKKRRG---GFAFVEMADLSSFQNAF 168
            |.||    |:|..:|::||:..|...|...|.:|.|. :..||.|   |:||:|........:|:
Human   101 AFKT----LFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAY 161

  Fly   169 Q-LHNTELQGRNIKVQIS----------------------------------------------- 185
            : ....::.||.:.|.:.
Human   162 KHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPS 226

  Fly   186 --------------------EAGKKKSANKKNIIKQKNRKLAEMRNEQKTFTKSGKFYDKDLKK- 229
                                |..|::...:.....::.|..:..:.|::...:..|..|:|.|:
Human   227 PLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRR 291

  Fly   230 -EKAKEMLARKRWRKK 244
             .:::|...|:|.||:
Human   292 SSRSRERARRERERKE 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3594	NP_523855.1	SF-CC1	36..>197	CDD:273721	35/225 (16%)
		RRM	116..187	CDD:440488	21/142 (15%)
SNRNP70	NP_003080.2	U1snRNP70_N	3..94	CDD:432406	9/57 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..79		7/40 (18%)
		Required for interaction with U1 RNA. /evidence=ECO:0000269|PubMed:2467746	92..202		24/113 (21%)
		RRM_snRNP70	102..187	CDD:409682	23/88 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..437		13/121 (11%)