DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3594 and Rbm34

DIOPT Version :9

Sequence 1:	NP_523855.1	Gene:	CG3594 / 37964	FlyBaseID:	FBgn0035063	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_766350.2	Gene:	Rbm34 / 52202	MGIID:	1098653	Length:	442	Species:	Mus musculus

Alignment Length:	278	Identity:	81/278 - (29%)
Similarity:	126/278 - (45%)	Gaps:	46/278 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASDSGSDYEVEAFFNPKRVQRTVNDDSADLLGNF----DDQKRREIF----------------- 44
            :|.|.|...::..  ||:. :|..|:.:. .:||.    :.:|.:..|
Mouse   166 LAKDGGQRTKIPV--NPEE-ERLKNERTV-FVGNLPVTCNKKKLKSFFKEYGQVESVRFRSVMPA 226

  Fly    45 EGTYVDKEDGRNPSDPEDSKSEDE--AKSDDEAAAEGSAASGAEEEESAENGQITSDQLSSLLRG 107
            |||...|..........|.||.:.  ...|:.|||:....:||   :.||..:|..|..|..
Mouse   227 EGTLTKKLAAIKRKFHPDQKSINAYVVFKDESAAAKALQRNGA---QIAEGFRIRVDLASET--- 285

  Fly   108 ASKTNRHVLYVTNLNFETTKDDLELHFSAAGTVKSIRI---PKKRRG-GFAFVEMADLSSFQNAF 168
            ||:..|.| :|.||.::.....||.||...|::.::||   |....| ||.:|...:..:...|.
Mouse   286 ASRDKRSV-FVGNLPYKIEDSALEEHFLDCGSIVAVRIVRNPLTGVGRGFGYVLFENTDAVHLAL 349

  Fly   169 QLHNTELQGRNIKVQIS---EAGKKKSAN---KKNIIKQKNRKLAEMRNEQKTFTKSGKFYDKD- 226
            :|:|:||.||.::|..|   |..|::::|   ||::||.|.| |.....|.|..:|.|||:.|:
Mouse   350 KLNNSELMGRKLRVMRSVNKEKLKQQNSNPSLKKDVIKPKQR-LNFTSKEGKFHSKEGKFHSKNA 413

  Fly   227 LKKEKAKEMLARKRWRKK 244
            ...|||..|..:|:.:||
Mouse   414 FIGEKAVLMKKKKKGQKK 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3594	NP_523855.1	RRM3_Prp24	114..184	CDD:240744	24/73 (33%)
Rbm34	NP_766350.2	RRM1_RBM34	189..280	CDD:240840	20/94 (21%)
Rbm34	NP_766350.2	RRM2_RBM34	292..364	CDD:240841	23/72 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2864
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23236
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960