DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3594 and CG3335

DIOPT Version :9

Sequence 1:	NP_523855.1	Gene:	CG3594 / 37964	FlyBaseID:	FBgn0035063	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_648337.1	Gene:	CG3335 / 39119	FlyBaseID:	FBgn0036018	Length:	918	Species:	Drosophila melanogaster

Alignment Length:	198	Identity:	43/198 - (21%)
Similarity:	81/198 - (40%)	Gaps:	55/198 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 PEDSKSEDEAKSDDEAAAEGSAASGAEEEESAENGQITSDQLSSLLRGASKTNRHVLYVTNLNFE 124
            ||:....::||.|:    |.|.|..|::|.....                     .|::.||||:
  Fly   650 PEEKPIVNDAKPDE----EDSRAEDADDEPEPNT---------------------TLFLRNLNFK 689

  Fly   125 TTKDDLELHFSAAGTVKSIRIPKKRRG---------GFAFVEMADLSSFQNAFQ-LHNTELQG-- 177
            |.::.:|.||...|::.::.|.|:|..         |:.|::....|..::|.: |..|.:.|
  Fly   690 TVQETVEKHFRHLGSIHTVEIAKRRDPENPREFKSLGYGFIQFKKSSVAEHALKNLQLTHIDGNP 754

  Fly   178 -------RNIKVQISEAGKKKSANKKNIIKQKNRKL--------AEMRNEQKTFTKSGKFYDKDL 227
                   |.:|.|.::..:::.|::|   ||...|:        |:.|..:..|...|:.....:
  Fly   755 VELKRSDRVLKTQDNDGAQRRLASQK---KQTGTKILVRNIPFQAQYREVRDIFKAFGELRSLRI 816

  Fly   228 KKE 230
            .|:
  Fly   817 PKK 819

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3594	NP_523855.1	RRM3_Prp24	114..184	CDD:240744	22/88 (25%)
CG3335	NP_648337.1	RRM1_RBM19	2..77	CDD:241008
		RRM_SF	250..314	CDD:302621
		RRM3_RBM19	362..440	CDD:241011
		RRM4_RBM19	552..623	CDD:241013
		RRM	<638..845	CDD:223796	43/198 (22%)
		RRM5_RBM19_like	679..760	CDD:240764	20/101 (20%)
		RRM6_RBM19	785..864	CDD:241015	6/35 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0110
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900