DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3594 and HNRNPA2B1

DIOPT Version :10

Sequence 1:NP_523855.1 Gene:CG3594 / 37964 FlyBaseID:FBgn0035063 Length:250 Species:Drosophila melanogaster
Sequence 2:NP_112533.1 Gene:HNRNPA2B1 / 3181 HGNCID:5033 Length:353 Species:Homo sapiens


Alignment Length:82 Identity:23/82 - (28%)
Similarity:39/82 - (47%) Gaps:8/82 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   116 LYVTNLNFETTKDDLELHFSAAGTVKS---IRIP-KKRRGGFAFVEMADLSSFQNAFQLHNTELQ 176
            |::..|:||||::.|..::...|.:..   :|.| .||..||.||..:.::....|.......:.
Human    23 LFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSID 87

  Fly   177 GRNIK----VQISEAGK 189
            ||.::    |...|:||
Human    88 GRVVEPKRAVAREESGK 104

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3594NP_523855.1 SF-CC1 36..>197 CDD:273721 23/82 (28%)
RRM 116..187 CDD:440488 20/78 (26%)
HNRNPA2B1NP_112533.1 Nuclear localization signal. /evidence=ECO:0000255 9..15
RRM1_hnRNPA2B1 19..99 CDD:410155 20/75 (27%)
RRM2_hnRNPA2B1 112..191 CDD:409995
Disordered. /evidence=ECO:0000269|PubMed:26544936 193..353
HnRNPA1 302..326 CDD:463312
Nuclear targeting sequence. /evidence=ECO:0000250 308..347
Blue background indicates that the domain is not in the aligned region.

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