DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment egg and SUVH4

DIOPT Version :9

Sequence 1:	NP_611966.3	Gene:	egg / 37962	FlyBaseID:	FBgn0086908	Length:	1262	Species:	Drosophila melanogaster
Sequence 2:	NP_196900.1	Gene:	SUVH4 / 831244	AraportID:	AT5G13960	Length:	624	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	136/523 - (26%)
Similarity:	203/523 - (38%)	Gaps:	133/523 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   753 TNAGGVSTSNSASAVRHLNNSTIYVDDENRPKGHV-VYFTAKRNLPPKMYKCHECSPNCLFKIVH 816
            |..||          .:|..:...:.|:...:|:: :....:.|:|.::.:.|    ||......
plant   220 TGQGG----------HNLTGNKRQIKDQLLERGNLALKHCCEYNVPVRVTRGH----NCKSSYTK 270

  Fly   817 RLDSYSPLAKPLLSGWERLVMRQKTKKSVVYKGPCGKSLRSLAEVHRY-LRATEN--VLNVDNFD 878
            |:.:|..|              .|.:|....||..|.:      |::| |:..|.  .|..|..:
plant   271 RVYTYDGL--------------YKVEKFWAQKGVSGFT------VYKYRLKRLEGQPELTTDQVN 315

  Fly   879 FTPDLKCLAEYSIDPSIVKDTDISKGQEKMAIPLVNYYDNTLPPPC---TYAKQRIPTEGVHLNL 940
            |.......:...|:..:.:  |||.|.|...||..|..|::...|.   ||.|..|....|   :
plant   316 FVAGRIPTSTSEIEGLVCE--DISGGLEFKGIPATNRVDDSPVSPTSGFTYIKSLIIEPNV---I 375

  Fly   941 DEEFLLCCDCEDDCSDKSKCACWQLTVAGVRY--CNPKKPIEEIGYQYKRLHEHVPTGIYECNSR 1003
            ..:....|:|...|:|..||||.:|......|  .|..:.||....            ::||...
plant   376 IPKSSTGCNCRGSCTDSKKCACAKLNGGNFPYVDLNDGRLIESRDV------------VFECGPH 428

  Fly  1004 CKCKKNCLNRVVQFSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHLLTETMANEGGQDAG 1068
            |.|...|:||..|..|...|:||:::.:||.:|....||.|:.:|.|.| ::..|...:...|
plant   429 CGCGPKCVNRTSQKRLRFNLEVFRSAKKGWAVRSWEYIPAGSPVCEYIG-VVRRTADVDTISD-- 490

  Fly  1069 DEYFADLDYIEVAEQLKEGYESEVDHSDPDAEEDNGGPDAEDDDDFRPNYHYQRKIKRSSRSGST 1133
            :||..::|    .:|..:|.               ||              .||:::  ..:...
plant   491 NEYIFEID----CQQTMQGL---------------GG--------------RQRRLR--DVAVPM 520

  Fly  1134 QNSSTQSSELDSQERAVINFNPNADLDETVRENSVRRLFGKDEAPYIMDAKTTGNLGRYFNHSCS 1198
            .|..:||||                 ||...|             :.:||.:|||..|:.||||.
plant   521 NNGVSQSSE-----------------DENAPE-------------FCIDAGSTGNFARFINHSCE 555

  Fly  1199 PNLFVQNVFVDTHDLRFPWVAFFSAAHIRSGTELTWNYNYEVGVVPG-----KVLYCQCGAPNCR 1258
            ||||||.|.....|:|...|..|:|.:|....|||::|.|.:..|.|     |.|.|.|||.|||
plant   556 PNLFVQCVLSSHQDIRLARVVLFAADNISPMQELTYDYGYALDSVHGPDGKVKQLACYCGALNCR 620

  Fly  1259 LRL 1261
            .||
plant   621 KRL 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
egg	NP_611966.3	HMT_MBD	823..879	CDD:238689	12/58 (21%)
		Pre-SET	901..1013	CDD:282838	32/116 (28%)
		SET	1022..1239	CDD:214614	58/216 (27%)
SUVH4	NP_196900.1	SAD_SRA	147..303	CDD:396656	22/116 (19%)
SUVH4	NP_196900.1	SET_AtSUVH-like	360..595	CDD:380943	85/317 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X219
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000