Protein Alignment egg and egg

DIOPT Version :10

• Sequence 1: NP_611966.3
• Gene: egg / 37962
• FlyBaseID: FBgn0086908
• Length: 1262
• Species: Drosophila melanogaster
• Sequence 2: XP_061518730.1
• Gene: egg / 1277970
• VectorBaseID: AGAMI1_007801
• Length: 1311
• Species: Anopheles gambiae
• Alignment Length: 1420
• Identity: 523/1420 - (36%)
• Similarity: 728/1420 - (51%)
• Gaps: 277/1420 - (19%)

  Fly     5 PTAVDCLESSGSTVEDVQETPASREKSYGLPVRKGENSLESPAEQAAKDVEIEELTHSEAIAATG 69
            |:|:..|||     ::..||.|..|.:..|.:.|.....|||:.:
Mosquito     7 PSAIISLES-----DEEMETNAESEATTELQLEKEPPHKESPSTE-------------------- 46

  Fly    70 STRKQCPYGGKAPDEPGKLA------------DESEDRKGENTKAIASSPVLVAVDSDSSVELIE 122
                ..|...||||....:.            ||.|....|..:..|....|...:..|..|
Mosquito    47 ----NVPSPSKAPDNASVVENAKDSEIICIDDDEKEPSVQETPEEKAPEEALPTAEPKSQPE--- 104

  Fly   123 SPVKFSSANESEKDP-------PKPDAVNEAAAKEAEEMTDSSISSPTSESFPEKDEKTNKENEQ 180
             ||..|.|   ||||       |:|.|..|..::..:|        |.|::..|.:.:|.||...
Mosquito   105 -PVPESQA---EKDPEPQAEKDPEPQAEKEPESQAEKE--------PESQAEREPESQTEKELGS 157

  Fly   181 EP---PGME--VDQDVEESISR----PAEEYKIENTLKGHKRISLTEIEEHKIVDKKDDVLEVEL 236
            :|   ||.|  .:|...||.|.    |.|   .||.      |:..::|..::|.|:|:|...:.
Mosquito   158 DPTKEPGSEPSKEQTAPESASNDTVPPLE---TENA------INDGDVEMQEVVQKEDEVKISDS 213

  Fly   237 EKGTAP------------------KAAEDEKLN-----------ALLSDGDVFYDK--------E 264
            :....|                  |.|:||..|           .::::|:....|        :
Mosquito   214 QPADPPAPPVSDGSQSVAMTDANNKQADDETANEQADKQNKQQEPVVTNGNADQPKKSKKPCAPK 278

  Fly   265 CVNCNCTKLHKQYVLANMATLNFYQVLRKSSKQQFLCMGCHDTAMDLYEEYAGQLMAKQPLLLKD 329
            |.|..|.|.:.|:..|....|:.|:| ..|.:.|.||..|.:.|:..||...|.|:..|||||.|
Mosquito   279 CCNTACKKKNVQFCDAPEFALSLYKV-PHSIQVQHLCYDCFEEAVSRYETLTGLLVNHQPLLLHD 342

  Fly   330 FHQDHAD-FVALDSSDEEEEEKQPEKSDFSKNK-------LQLIEDELDDAIKNVLNKVDFTAQL 386
            ...|.|: .:.|||||||:|:...|:    ||:       :.|:|.:|||.|..:...:... |:
Mosquito   343 NQPDVAEILMVLDSSDEEDEDTVIER----KNEPALPAEAVSLVESDLDDVIYKLYGSLCLD-QI 402

  Fly   387 SWSKTIL-------QAKADHLERQF-----ALADVE--LEKVQTT-ADKMHCALYN---SCPVAH 433
            .||.:||       ||.:|.:|.|.     |..|::  :..|:|| .||....:.:   |..:||
Mosquito   403 KWSNSILLHEAEQNQATSDRIEAQMKTLKSAFQDIQNNIYSVRTTKIDKPELIIEDDATSEQIAH 467

  Fly   434 KHLPTLDIEPSDYVHEVPPPGEIVRPPIQLGETYYAVKNKAIASWVSIKVIEFTESTAINGNTMK 498
            :...:: :..::.:|         |.|:|:|..|:.|:...:|||...||:|           :|
Mosquito   468 ERFRSM-LSKTETLH---------REPVQVGCQYFGVRTTVLASWTECKVLE-----------VK 511

  Fly   499 S--YKIRYL-NTPYQMIKTVTAKHIAYFEPPPVRLTIGTRVIAYFDGTTLSRGKDKGVVQSAFYP 560
            |  |.:|:| ..|...:  :||||:||..||.|:|.:||||:|    .|.|..:|.  :...||.
Mosquito   512 SDMYTVRFLTGDPKPTV--ITAKHLAYTTPPNVKLLLGTRVVA----RTSSATQDG--MNRTFYA 568

  Fly   561 GIIAEPLKQANRYRYLIFYDDGYTQYVPHRDVRLVCQASEKVWEDVHAASRDFIQKYVEKYSVDR 625
            |.:.|.|...|:|||||..|.|:.||.|..|||:||..|:.||:|||..||:||:.|:.|....|
Mosquito   569 GTVLESLSSYNKYRYLIVLDSGHPQYSPFTDVRVVCDQSKHVWDDVHPHSREFIRNYMLKSGSVR 633

  Fly   626 PMVQCTRGQSMTTESNGTWLYARVIDIDCSLVLMQFEGDKNHTEWIYRGSLRLGPVFRETQNNMN 690
            ||||..|||.|..|.:..|....|::.|.|||.:.|.| ....|||||||.||.|::|.. |..:
Mosquito   634 PMVQAHRGQRMMVEIDDKWFQGTVLETDSSLVRLYFSG-MERKEWIYRGSSRLAPLYRGV-NTGH 696

  Fly   691 SSSAQQLRVPRRTEPFIRY-TKEMESSSK--------VNQQ-----------MRAFARKSSASAQ 735
            :.:.:..:..:|.||.|.| |.|.:.|.:        :|.|           .||.||||:|:
Mosquito   697 APNNKFSKFQKRNEPSIEYITLEDDDSEQPPEKKAATINYQPAPKMEIPDTPNRATARKSTAN-- 759

  Fly   736 NNALAAASSAATPAGGRT-NAGGVSTSNSASAVRHLNNSTIYVD-DENRPKGHVVYFTAKRNLPP 798
                            || |...::.:|:...  .||.:|||:| |:::..|..:.:|.|....|
Mosquito   760 ----------------RTLNNHNINNNNNVPV--SLNRNTIYIDCDQDQSNGRTLLYTTKNYRGP 806

  Fly   799 KMYKCHECSPNCLFKIVHRLDSYSPLAKPLLSGWER--LVMRQKTKKSVVYKGPCGKSLRSLAEV 861
            :.:..|.|.|:|.:|....|.||:.||:||::||||  ...|.:.|..|:|:.|||:.||::||:
Mosquito   807 RKFVPHNCGPSCPYKGGKNLRSYNLLARPLITGWERHKTAARGQKKSVVLYRAPCGRRLRNMAEL 871

  Fly   862 HRYLRATENVLNVDNFDFTPDLKCLAEYSIDPSIVKDTDISKGQEKMAIPLVNYYDNTLPPPCTY 926
            |:|||.|::.|||::|||.||::.||.:..:....:.||:|.|.|.|.:..||.|||..||.|.|
Mosquito   872 HQYLRVTDSPLNVEHFDFDPDIRALATFKAENVFFECTDLSFGLEPMPVHCVNNYDNKQPPSCEY 936

  Fly   927 AKQRIPTEGVHLNLDEEFLLCCDCEDDCSDKSKCACWQLTVAGVRY-CNPKKPIEEIGYQYKRLH 990
            :.:|||||||:||||:|||..|||||||:|||||.|||||:||.:| ....:.|..:||.||||.
Mosquito   937 STERIPTEGVNLNLDKEFLCGCDCEDDCTDKSKCQCWQLTLAGAKYGLKENQDINTVGYHYKRLM 1001

  Fly   991 EHVPTGIYECNSRCKCKKN-CLNRVVQFSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHL 1054
            .|:.|||||||.:|||||: |||||||.||:.|||||.|.|:|||:||:||:|||:|||||||||
Mosquito  1002 SHLSTGIYECNVQCKCKKDKCLNRVVQNSLQTKLQVFNTHNKGWGIRCLNDVPKGSFICIYAGHL 1066

  Fly  1055 LTETMANE----GGQDAGDEYFADLDYIEVAEQLKEGYESEVDHSD----------------PDA 1099
            |||..:|.    ....:|||||||||:||..|:.|..||:|...||                .||
Mosquito  1067 LTEETSNRICAMSDDKSGDEYFADLDFIETVEKSKADYEAEAYQSDREDSTPAGNANDSDASDDA 1131

  Fly  1100 EEDNGGPDAEDDDDFRPNYHYQRKIKRS-----SRSGSTQNSSTQ-----------SSELDSQER 1148
            .|:...|...|.|:     .|..|.|.|     :|:...:.|:|:           |::..:.|:
Mosquito  1132 IENGPSPSTHDSDE-----EYTTKSKPSGTVVKTRAQLRKASTTERPNAAMFGKKSSNDGVNDEQ 1191

  Fly  1149 AVINFNPNADLDETVR------ENSVRRLFGKDEAPYIMDAKTTGNLGRYFNHSCSPNLFVQNVF 1207
            ..:|..||.::|....      |:..|:|:|::|..|:||||.:|||||||||||:|||||||||
Mosquito  1192 ECVNLIPNPEMDMMDASGGPNDESLFRKLYGENEHIYVMDAKKSGNLGRYFNHSCNPNLFVQNVF 1256

  Fly  1208 VDTHDLRFPWVAFFSAAHIRSGTELTWNYNYEVGVVPGKVLYCQCGAPNCRLRLL 1262
            ||||||||||||||:..:|.:||||||||||:||.|.||.|.|.||...|:.|||
Mosquito  1257 VDTHDLRFPWVAFFAERNITAGTELTWNYNYDVGSVNGKHLTCNCGEKGCKGRLL 1311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
egg	NP_611966.3	Tudor_SETDB1_rpt1	532..622	CDD:410453	41/89 (46%)
		Tudor_SETDB1_rpt2	630..684	CDD:410548	23/53 (43%)
		HMT_MBD	823..879	CDD:238689	28/57 (49%)
		SET_SETDB1	900..1262	CDD:380915	210/405 (52%)
egg	XP_061518730.1	None