DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment egg and LOC103910708

DIOPT Version :9

Sequence 1:	NP_611966.3	Gene:	egg / 37962	FlyBaseID:	FBgn0086908	Length:	1262	Species:	Drosophila melanogaster
Sequence 2:	XP_017210664.2	Gene:	LOC103910708 / 103910708	-ID:	-	Length:	534	Species:	Danio rerio

Alignment Length:	443	Identity:	88/443 - (19%)
Similarity:	143/443 - (32%)	Gaps:	140/443 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 VLVAVDSDSSVEL-IESPVKFSSANESEKDPPKPD-AVNEAAAKEAEEMTDSSISSP---TSESF 167
            ||..:.|..|.|: :|...|.|.....::..||.. ||.|||.|:.:.:. ..:..|   |.:..
Zfish   126 VLYGIQSGMSKEVSMEVTAKKSEFGCGKEVLPKDCLAVLEAAFKDFQAVI-CKMQGPGAITGDCL 189

  Fly   168 PEKDEKTNKENEQ----------------EPPGMEVDQDVEESISRPAEEYKIENTLKGHKRISL 216
                    .:|||                :.||:.....||:...|.    :|||.:       .
Zfish   190 --------TKNEQLLVLYYLEAVIMLKLVQRPGIVTHMTVEDWEGRS----RIENGV-------C 235

  Fly   217 TEIEEHKIVDKKDDVLEVEL-----------EKGTAPKAAEDEKLNALLSDGDVFYDKECVNCNC 270
            ..::|||:....:..|...|           |..|....|.|...  :.|.|...|:.   :.:.
Zfish   236 VAVKEHKVPLSHEQELWFNLYFNEVRPVMLQENHTDDDVAVDSFF--VSSSGRSIYNP---SNDL 295

  Fly   271 TKLHKQYVLANMATLNFYQVLRKSSKQQFLCMGCHDTAMDLYEEYAGQL------MAKQPLLLKD 329
            .:||.:|.|.::.                    |.| |...:|..|..|      :|.:...::.
Zfish   296 KRLHDKYSLPSVT--------------------CGD-AQRAFEAAAQSLSEVERNVAAERNYMRG 339

  Fly   330 FHQDHADFVALDSSDEEEEEKQPEKSDFSKNKLQLIEDELDD--AIKNVLNKVDFTAQ------- 385
            ...|  .|:||...| :...|.|::|    :|....|..:|:  |.|.:......|.:
Zfish   340 TSSD--PFLALSVLD-QLAGKTPQRS----SKASCCETRVDEQTAYKTLEQFCPVTLEGPPPKRA 397

  Fly   386 ---------------LSWSKTILQAKADHLERQFALADVELEKVQTTADKMHCALYNSCPVA--- 432
                           ..|....|:.:..|....||.......|:....||.  ...::.|.|
Zfish   398 RRTELCGSEHERHCYDRWRSEQLKLREQHALEHFAGQQPSESKINRWMDKQ--GWTSNVPQAAVV 460

  Fly   433 ---HKHLPTLDIE-PSDYVHEV------------PPP----GEIVRPPIQLGE 465
               .|.:..||:: .|.:|.::            |.|    |...:.|.|:||
Zfish   461 LKQWKPVARLDLDIDSSFVKKIILSQRWKGLTVRPVPDKGDGVFTKRPFQIGE 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
egg	NP_611966.3	HMT_MBD	823..879	CDD:238689
		Pre-SET	901..1013	CDD:282838
		SET	1022..1239	CDD:214614
LOC103910708	XP_017210664.2	SET	491..>531	CDD:214614	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593777
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930