DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment egg and Kmt2b

DIOPT Version :9

Sequence 1:	NP_611966.3	Gene:	egg / 37962	FlyBaseID:	FBgn0086908	Length:	1262	Species:	Drosophila melanogaster
Sequence 2:	XP_038949797.1	Gene:	Kmt2b / 102550344	RGDID:	7678027	Length:	2714	Species:	Rattus norvegicus

Alignment Length:	125	Identity:	39/125 - (31%)
Similarity:	53/125 - (42%)	Gaps:	29/125 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1156 NADLDETVRENS---VRRLF---------GKDEAPY--------IMDAKTTGNLGRYFNHSCSPN 1200
            |.|..|.|.|.|   :|.:.         ||....|        ::||...||..|:.||||.||
  Rat  2593 NIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPN 2657

  Fly  1201 LFVQNVFVD--THDLRFPWVAFFSAAHIRSGTELTWNYNYEVGVVPGKVLYCQCGAPNCR 1258
            .|.:.:.|:  .|      :..|:...|..|.|||::|.:.:.....| |.|.|||..||
  Rat  2658 CFSRVIHVEGQKH------IVIFALRRILRGEELTYDYKFPIEDASNK-LPCNCGAKRCR 2710

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
egg	NP_611966.3	HMT_MBD	823..879	CDD:238689
		Pre-SET	901..1013	CDD:282838
		SET	1022..1239	CDD:214614	31/104 (30%)
Kmt2b	XP_038949797.1	zf-CXXC	956..1003	CDD:366873
		PHD1_KMT2B	1202..1248	CDD:277064
		PHD2_KMT2B	1250..1299	CDD:277066
		PHD3_KMT2B	1336..1392	CDD:277068
		Bromo_ALL-1	1373..1515	CDD:99925
		ePHD_KMT2B	1580..1684	CDD:277164
		FYRN	1732..1779	CDD:399155
		PHA03247	<1807..2315	CDD:223021
		FYRC	2412..2496	CDD:197781
		SET_KMT2A_2B	2561..2714	CDD:380947	39/125 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351973
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930