Sequence 1: | NP_611965.2 | Gene: | Eps-15 / 37961 | FlyBaseID: | FBgn0035060 | Length: | 1253 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001185897.1 | Gene: | Itsn2 / 20403 | MGIID: | 1338049 | Length: | 1685 | Species: | Mus musculus |
Alignment Length: | 1220 | Identity: | 254/1220 - (20%) |
---|---|---|---|
Similarity: | 422/1220 - (34%) | Gaps: | 430/1220 - (35%) |
- Green bases have known domain annotations that are detailed below.
Fly 116 PVASGGVANGDWSIGVIDRLKYEQLFESLHPSNGMLPGNKVKGVLMDSKLPMSILGTIWDLADQD 180
Fly 181 KDGNLDMHEFVVAMHLVYQTLQKRTIPSVLPPELRKPG----------GAGPPP-----KPAMPP 230
Fly 231 PPAGAAMPRAPSGEGFGDGGFVANFPKDIAPPAAIPPL--------------PVAVPPMTRIPP- 280
Fly 281 -------VGAVSSQPLIQTDPLIPIG--------------APVMANADWVVTPADLKRFEEIFRQ 324
Fly 325 SDLDKDGLVSGLEVKDIFIKSGIPQRSLADIWALCDTNQSGKLTVEQFALAMWFVERKQRGVDPP 389
Fly 390 HVLNANMVPPSMRA-----TVAGV--------DLQPQEVKP-TY----------SNPELE----- 425
Fly 426 -----------MISKEIEELARERRVLETEIAQKEADVRIKNGEVRSLQ--------SELDTLTA 471
Fly 472 TLKQLENQRGEAQKRL--DDLQAQVSHNTAVLANVS-------LDISRTN---EQVT-KIRD--- 520
Fly 521 --------------QCHMQEVTINEQEGEL----------------------------------- 536
Fly 537 -----NAKRSEL-QKLKDEEASLQKEYDSNNRELSKLTNHLQATQLQISSVRSMVTQ-LLETQRQ 594
Fly 595 MTDALLICRAAMENQNAELVSEYQL-KIEPD------------------FDEA------------ 628
Fly 629 RKTLTKE---------VQLPKDDPFEENNSGAANQA------TNGFGSDPFSGQPVNKPAISTGF 678
Fly 679 DDSFNMSSGFDSGFDAFGQSGAGSAFGQTQRDPFGSDAFAANKSNAITPEPGKDDFGSDPFAALH 743
Fly 744 APTGQGQVLSPNAQKSGPPPRPESPSPALPPKKSKVPPPRPAPPRAAQPTGGFGSGGGGGFADFD 808
Fly 809 DFDNKLHHIPSAPSPSATALSPLPPTLPAPIPVVSGSSLLDSFTLFDDPGQIHKQAASTPNPTPI 873
Fly 874 TVPTVHTLLQTSLSTPAAPSPALASLSTSGSGSVAGAGADLPSSVTIT-TAPSLNNQHLSRSNTP 937
Fly 938 LQNQRTADVKLETKAVVSVFDA-----FGEIGTRKAPTP----SLITGPTDFKDDPFKDYR--YE 991
Fly 992 DPFSIKDPFAEE----GEEELSEGKGADHKRNFAE----DFSSGDEI-----------GSAAKTL 1037
Fly 1038 SNIVNNNSIKPKAATPLNNDLLQQFDAFNLNSSPAPSHHSGTSYHSNSKP 1087 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Eps-15 | NP_611965.2 | EH | 16..82 | CDD:238009 | |
EH | 126..215 | CDD:197477 | 34/88 (39%) | ||
EH | 137..202 | CDD:238009 | 23/64 (36%) | ||
EH | 307..402 | CDD:197477 | 29/94 (31%) | ||
EH | 318..384 | CDD:238009 | 20/65 (31%) | ||
RILP-like | <445..548 | CDD:304877 | 27/181 (15%) | ||
Spc24 | 529..>584 | CDD:285486 | 17/95 (18%) | ||
Itsn2 | NP_001185897.1 | EH | 15..107 | CDD:197477 | 34/91 (37%) |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 220..242 | 2/21 (10%) | |||
EH | 238..317 | CDD:197477 | 22/78 (28%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 335..382 | 10/46 (22%) | |||
Smc | 350..>747 | CDD:224117 | 75/401 (19%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 716..742 | 5/25 (20%) | |||
SH3_Intersectin2_1 | 747..803 | CDD:212921 | 16/94 (17%) | ||
INTAP | 806..883 | CDD:374674 | 29/161 (18%) | ||
SH3_Intersectin2_2 | 883..934 | CDD:212923 | 10/67 (15%) | ||
SH3_Intersectin2_3 | 973..1024 | CDD:212925 | 10/56 (18%) | ||
SH3_Intersectin2_4 | 1045..1103 | CDD:212927 | |||
SH3_Intersectin2_5 | 1118..1171 | CDD:212929 | |||
RhoGEF | 1202..1381 | CDD:366202 | |||
PH_13 | 1400..1554 | CDD:374702 | |||
C2_Intersectin | 1543..1677 | CDD:176021 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C167844363 | |
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 1 | 1.000 | - | - | ||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.840 |