DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstE12 and EEF1E1

DIOPT Version :9

Sequence 1:NP_001246500.1 Gene:GstE12 / 37960 FlyBaseID:FBgn0027590 Length:223 Species:Drosophila melanogaster
Sequence 2:NP_004271.1 Gene:EEF1E1 / 9521 HGNCID:3212 Length:174 Species:Homo sapiens


Alignment Length:189 Identity:41/189 - (21%)
Similarity:66/189 - (34%) Gaps:51/189 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 AKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTL-IDGEATIIDSHAICAYLVEKYGQKEQQ 85
            |.|..|.|..:.:.|.||...:.:     .:..||.| .:...::.....|.|:|| |...||..
Human     2 AAAAELSLLEKSLGLSKGNKYSAQ-----GERQIPVLQTNNGPSLTGLTTIAAHLV-KQANKEYL 60

  Fly    86 L----YPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYGSTDCSIDKIAYIQKCWEILEGFL 146
            |    ..|.:||:. ::.|:....||              ....|        |....:.|..:|
Human    61 LGSTAEEKAIVQQW-LEYRVTQVDGH--------------SSKND--------IHTLLKDLNSYL 102

  Fly   147 KDQPYLCGSDLTIAD---------FCAVATVTSVNDTAPIDEFKFPKMHAWLKRLAELP 196
            :|:.||.|.:.|:||         |....||.        ::.|:..:..|...:...|
Human   103 EDKVYLTGYNFTLADILLYYGLHRFIVDLTVQ--------EKEKYLNVSRWFCHIQHYP 153

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstE12NP_001246500.1 GST_N_Delta_Epsilon 4..77 CDD:239343 13/55 (24%)
GstA 6..201 CDD:223698 41/189 (22%)
GST_C_Delta_Epsilon 92..210 CDD:198287 22/114 (19%)
EEF1E1NP_004271.1 N-terminal 2..56 15/59 (25%)
Linker 57..63 3/5 (60%)
C-terminal 64..152 22/118 (19%)
GST_C_AIMP3 65..165 CDD:198338 23/120 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0625
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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