DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE12 and Clic4

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_114006.1	Gene:	Clic4 / 83718	RGDID:	61857	Length:	253	Species:	Rattus norvegicus

Alignment Length:	194	Identity:	37/194 - (19%)
Similarity:	62/194 - (31%)	Gaps:	88/194 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LDLELRPI---NLLKGEH-------------------------LTPEFLKLNPQHTIPTLIDGEA 63
            :||:.:|.   ||..|.|                         ..|::|||:|:|.     :...
  Rat    57 VDLKRKPAHLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHP-----ESNT 116

  Fly    64 TIIDSHA-ICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYGSTDC 127
            ..:|..| ..||:      |..:....|.::|..:.....||        .:|..|:
  Rat   117 AGMDIFAKFSAYI------KNSRPEANEALERGLLKTLQKLD--------EYLNSPL-------- 159

  Fly   128 SIDKIAYIQKCWEILEGFLKD-----QPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMH 186
                      ..||.|..::|     :.:|.|.::|:|| |.:                .||:|
  Rat   160 ----------PGEIDENSMEDIKSSTRRFLDGDEMTLAD-CNL----------------LPKLH 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	17/78 (22%)
		GstA	6..201	CDD:223698	37/194 (19%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	18/100 (18%)
Clic4	NP_114006.1	Required for insertion into the membrane. /evidence=ECO:0000250	2..101		7/43 (16%)
		GST_N_CLIC	14..104	CDD:239359	8/46 (17%)
		O-ClC	17..252	CDD:129941	37/194 (19%)
		GST_C_family	111..251	CDD:295467	25/140 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347860
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930