DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE12 and Clic3

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	XP_030107910.1	Gene:	Clic3 / 69454	MGIID:	1916704	Length:	268	Species:	Mus musculus

Alignment Length:	194	Identity:	34/194 - (17%)
Similarity:	55/194 - (28%)	Gaps:	73/194 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PINLLKGEHLT---------------PEFLKLNPQHTIPTLIDGEATIIDSHAICAYLVEKYGQK 82
            ||.|..|:..|               |:|..|.|::........:.    .|...|::......:
Mouse    95 PILLYDGDVKTDTLQIEEFLEETLGPPDFPSLAPRYRESNTAGNDI----FHKFSAFIKNPVPTQ 155

  Fly    83 EQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYGSTDCSIDKIAYIQKCWEILEGFLK 147
            :..||.:.|.....:|:.|.....|..|:...|.|                             .
Mouse   156 DNALYQQLLRALTRLDSYLRAPLDHELAQEPHLRE-----------------------------S 191

  Fly   148 DQPYLCGSDLTIADFCAVATVTSVNDTA-------PI-----------------DEFKFPKMHA 187
            .:.:|.|...|:|| |::.....:.||.       ||                 .|||:...|:
Mouse   192 HRRFLDGDQFTLAD-CSLLPKLHIVDTVCAHFRQLPIPAELSCVRRYLDSALQKKEFKYTCPHS 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	11/58 (19%)
		GstA	6..201	CDD:223698	34/194 (18%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	20/120 (17%)
Clic3	XP_030107910.1	O-ClC	43..261	CDD:129941	34/194 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844736
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930