DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE12 and CLIC5

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_001107558.1	Gene:	CLIC5 / 53405	HGNCID:	13517	Length:	410	Species:	Homo sapiens

Alignment Length:	168	Identity:	42/168 - (25%)
Similarity:	61/168 - (36%)	Gaps:	63/168 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 KGEHLTPE---FLKLNPQHTIPTLIDGEATIIDSHAICAYLVEKYGQKEQQLYP----KELV-QR 94
            :|.|:.||   |:|..        ||||     |...|.:        .|:|:.    |.:| ..
Human   167 EGAHMNPEIYLFVKAG--------IDGE-----SIGNCPF--------SQRLFMILWLKGVVFNV 210

  Fly    95 ANVD-----ARLH-LDSGHLFARLRFLYEPIL-YYGSTDCSIDKIAYIQKCWEILEGFLKDQPYL 152
            ..||     |.|| |..|        .:.|.| :.|.....::||          |.||::
Human   211 TTVDLKRKPADLHNLAPG--------THPPFLTFNGDVKTDVNKI----------EEFLEE---- 253

  Fly   153 CGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMHAWLK 190
               .||...:..:|.....::||.||.|.  |..|::|
Human   254 ---TLTPEKYPKLAAKHRESNTAGIDIFS--KFSAYIK 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	12/41 (29%)
		GstA	6..201	CDD:223698	42/168 (25%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	27/107 (25%)
CLIC5	NP_001107558.1	O-ClC	173..408	CDD:129941	40/162 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930