DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE12 and GstD7

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_525114.1	Gene:	GstD7 / 48340	FlyBaseID:	FBgn0010043	Length:	224	Species:	Drosophila melanogaster

Alignment Length:	214	Identity:	82/214 - (38%)
Similarity:	125/214 - (58%)	Gaps:	14/214 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLIDGEATIIDSHA 70
            ||...::|.|||:.:.|||:||:|..:.||.::|:.|.|||:::|||||||||:|....|.:|.|
  Fly     6 LYNFPMAPASRAIQMVAKALGLELNSKLINTMEGDQLKPEFVRINPQHTIPTLVDNGFVIWESRA 70

  Fly    71 ICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLR---FLYEPILYYGSTDCSIDKI 132
            |..|||||||:.:..|||.:..:||.::.||:.|.|.|:..|.   ||......:|..: ::||
  Fly    71 IAVYLVEKYGKPDSPLYPNDPQKRALINQRLYFDMGTLYDALTKYFFLIFRTGKFGDQE-ALDK- 133

  Fly   133 AYIQKCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMHAWLKRLAELPY 197
              :...:..|..||:.|.::.||.||:||...:|||::| :....|..|||.:..|||...::..
  Fly   134 --VNSAFGFLNTFLEGQDFVAGSQLTVADIVILATVSTV-EWFSFDLSKFPNVERWLKNAPKVTP 195

  Fly   198 YQEVNGDGADELKSIFKAK 216
            ..|.|      |:|:.:.|
  Fly   196 GWEQN------LESLQQGK 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	35/70 (50%)
		GstA	6..201	CDD:223698	77/197 (39%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	36/120 (30%)
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	35/70 (50%)
		GstA	6..188	CDD:223698	75/186 (40%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	38/124 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460338
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800