DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE12 and GstD6

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_524915.1	Gene:	GstD6 / 48339	FlyBaseID:	FBgn0010042	Length:	215	Species:	Drosophila melanogaster

Alignment Length:	219	Identity:	83/219 - (37%)
Similarity:	124/219 - (56%)	Gaps:	15/219 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLIDGEATIIDSHA 70
            ||..:.||.:|||::||||:|::.....:|...||.|.|.|:|:|||||||||:|....|.::.|
  Fly     3 LYNMSGSPSTRAVMMTAKAVGVEFNSIQVNTFVGEQLEPWFVKINPQHTIPTLVDNLFVIWETRA 67

  Fly    71 ICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYG--STDCSIDKIA 133
            |..||||:|| |:..||||:..::|.::.||:.|.|.|:..:...:.|:|..|  .|..:::|
  Fly    68 IVVYLVEQYG-KDDSLYPKDPQKQALINQRLYFDMGTLYDGIAKYFFPLLRTGKPGTQENLEK-- 129

  Fly   134 YIQKCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMHAWLKRLAELPYY 198
             :...:::|..||..|.|:.|:.|::||...:||| |..:....|..|||.:..|.|..
  Fly   130 -LNAAFDLLNNFLDGQDYVAGNQLSVADIVILATV-STTEMVDFDLKKFPNVDRWYKNA------ 186

  Fly   199 QEVNGDGADELKSIFKAK--LAEN 220
            |:|.....:.|..|..||  ||||
  Fly   187 QKVTPGWDENLARIQSAKKFLAEN 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	34/70 (49%)
		GstA	6..201	CDD:223698	74/196 (38%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	32/119 (27%)
GstD6	NP_524915.1	GST_N_Delta_Epsilon	1..74	CDD:239343	34/70 (49%)
		PLN02395	11..208	CDD:166036	75/207 (36%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	34/125 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460325
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800