DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE12 and GstD5

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_524914.3	Gene:	GstD5 / 48338	FlyBaseID:	FBgn0010041	Length:	216	Species:	Drosophila melanogaster

Alignment Length:	215	Identity:	83/215 - (38%)
Similarity:	123/215 - (57%)	Gaps:	9/215 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLIDGEATIIDSHAI 71
            ||:......|.|::.|||:|:.|.::.:|.|:.:.|.|||:|||||||||||:|...:|.:|.||
  Fly     4 YYSPRGSGCRTVIMVAKALGVKLNMKLLNTLEKDQLKPEFVKLNPQHTIPTLVDNGFSIWESRAI 68

  Fly    72 CAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYGSTDCSIDKIAYIQ 136
            ..||||||| |:..|:||:..::|.|:.||:.|.|.|:......|.|:.:.|... |.:....|:
  Fly    69 AVYLVEKYG-KDDTLFPKDPKKQALVNQRLYFDMGTLYDSFAKYYYPLFHTGKPG-SDEDFKKIE 131

  Fly   137 KCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEF---KFPKMHAWLKRLAELPYY 198
            ..:|.|..||:.|.|:.|..||:||...::||:    |..|.:|   |:|.:..|.....::...
  Fly   132 SSFEYLNIFLEGQNYVAGDHLTVADIAILSTVS----TFEIFDFDLNKYPNVARWYANAKKVTPG 192

  Fly   199 QEVNGDGADELKSIFKAKLA 218
            .|.|..||.|||.:|.|:.|
  Fly   193 WEENWKGAVELKGVFDARQA 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	33/69 (48%)
		GstA	6..201	CDD:223698	73/196 (37%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	36/120 (30%)
GstD5	NP_524914.3	GstA	1..184	CDD:223698	73/185 (39%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	33/69 (48%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	36/120 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460234
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800