DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE12 and GstD11

DIOPT Version :9

Sequence 1:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_001138040.1	Gene:	GstD11 / 41512	FlyBaseID:	FBgn0038029	Length:	243	Species:	Drosophila melanogaster

Alignment Length:	232	Identity:	87/232 - (37%)
Similarity:	130/232 - (56%)	Gaps:	20/232 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKPALYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLIDGEATI 65
            ||.|.|||...|||.|::||.||.:.:|.||:.:|:|:||.|.|:|:.:||||.:||:.|....:
  Fly    22 MSPPVLYYLPPSPPCRSILLLAKMLDIDFELKIVNILEGEQLKPDFVAMNPQHCVPTMNDEGLVL 86

  Fly    66 IDSHAICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYGSTDCSID 130
            .:|.||.:|||..|| |..||||.::..||.||.||..|.|.|:.||...|.|.::.|:   .:|
  Fly    87 WESRAILSYLVAAYG-KSDQLYPTDIRVRALVDQRLQFDLGTLYMRLTDYYFPTMFIGA---PLD 147

  Fly   131 --KIAYIQKCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKF---PKMH--AW 188
              |.|.:.:....|...|:.:.:......||||...:.||:.      ::.|:|   |..|  .|
  Fly   148 EGKRAKLAEAVGWLNTILEGRQFSAADHFTIADLTLLVTVSQ------LEAFEFELRPYKHIRQW 206

  Fly   189 LKRLAE--LPY-YQEVNGDGADELKSIFKAKLAENRG 222
            |.|..:  .|: |:|:|.:.|:.|..:||||:.::.|
  Fly   207 LDRCKDHMAPFDYEELNANKANMLADMFKAKMNQSAG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	34/72 (47%)
		GstA	6..201	CDD:223698	75/204 (37%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	37/127 (29%)
GstD11	NP_001138040.1	GST_N_Delta_Epsilon	25..98	CDD:239343	34/72 (47%)
GstD11	NP_001138040.1	GST_C_Delta_Epsilon	112..231	CDD:198287	37/127 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	9	8.970